Review of the existing maximum residue levels for clethodim according to Article 12 of Regulation (EC) No 396/2005.

3‐chloroallyl alcohol glucoside MRL review Regulation (EC) No 396/2005 clethodim consumer risk assessment cyclohexene oxime herbicide

Journal

EFSA journal. European Food Safety Authority
ISSN: 1831-4732
Titre abrégé: EFSA J
Pays: United States
ID NLM: 101642076

Informations de publication

Date de publication:
May 2019
Historique:
entrez: 7 7 2020
pubmed: 22 5 2019
medline: 22 5 2019
Statut: epublish

Résumé

According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance clethodim. To assess the occurrence of clethodim residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission and European authorisations reported by Member States (including the supporting residues data). Based on the assessment of the available data, MRL could not be proposed because an overall consumer risk assessment could not be finalised. Risk managers should be made aware that the genotoxic potential of the clethodim metabolite 3-chloroallyl alcohol, the aglycon of 3-chlorolallyl alcohol glucoside (M14A/M15A) could not be concluded and no toxicological reference values could be derived for this metabolite. Until a conclusion on the toxicological properties of the metabolite is reached, a decision on the residue definition for risk assessment cannot be made which is a prerequisite to perform a reliable dietary risk assessment.

Identifiants

pubmed: 32626327
doi: 10.2903/j.efsa.2019.5706
pii: EFS25706
pmc: PMC7009186
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e05706

Informations de copyright

© 2019 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

Auteurs

Classifications MeSH