Combination of DCE-MRI and DWI in Predicting the Treatment Effect of Concurrent Chemoradiotherapy in Esophageal Carcinoma.
Journal
BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
04
2019
revised:
26
12
2019
accepted:
30
01
2020
entrez:
7
7
2020
pubmed:
7
7
2020
medline:
2
4
2021
Statut:
epublish
Résumé
Concurrent chemoradiotherapy (CCRT) is the main treatment for esophageal cancer, but the response to treatment varies from individual to individual. MR imaging methods, such as diffusion-weighted (DW) MRI and the use of dynamic contrast-enhanced (DCE) MRI, have the potential to provide additional biomarkers that could evaluate the effect of CCRT in patients with esophageal carcinoma. Fifty-six patients with esophageal carcinoma, verified by histopathology, underwent MRI examination before and at midtreatment (4 56 patient MRI scans were available for analysis at baseline and at the third week, respectively. Pretreatment The combination of DCE and DWI can be used as an early biomarker in the prediction of the effect of CCRT three weeks after treatment in esophageal carcinoma.
Sections du résumé
BACKGROUND
BACKGROUND
Concurrent chemoradiotherapy (CCRT) is the main treatment for esophageal cancer, but the response to treatment varies from individual to individual. MR imaging methods, such as diffusion-weighted (DW) MRI and the use of dynamic contrast-enhanced (DCE) MRI, have the potential to provide additional biomarkers that could evaluate the effect of CCRT in patients with esophageal carcinoma.
MATERIALS AND METHODS
METHODS
Fifty-six patients with esophageal carcinoma, verified by histopathology, underwent MRI examination before and at midtreatment (4
RESULTS
RESULTS
56 patient MRI scans were available for analysis at baseline and at the third week, respectively. Pretreatment
CONCLUSION
CONCLUSIONS
The combination of DCE and DWI can be used as an early biomarker in the prediction of the effect of CCRT three weeks after treatment in esophageal carcinoma.
Identifiants
pubmed: 32626736
doi: 10.1155/2020/2576563
pmc: PMC7315287
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2576563Informations de copyright
Copyright © 2020 Changmin Liu et al.
Déclaration de conflit d'intérêts
No potential conflicts of interest were disclosed.
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