An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group.
Journal
European heart journal
ISSN: 1522-9645
Titre abrégé: Eur Heart J
Pays: England
ID NLM: 8006263
Informations de publication
Date de publication:
01 10 2020
01 10 2020
Historique:
received:
03
02
2020
revised:
29
05
2020
accepted:
01
06
2020
pubmed:
7
7
2020
medline:
15
5
2021
entrez:
7
7
2020
Statut:
ppublish
Résumé
This consensus document, a summary of the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI), appraises the importance of ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% of patients undergoing invasive angiography do not have obstructive coronary artery disease, more common in women than in men, and a large proportion have INOCA as a cause of their symptoms. INOCA patients present with a wide spectrum of symptoms and signs that are often misdiagnosed as non-cardiac leading to under-diagnosis/investigation and under-treatment. INOCA can result from heterogeneous mechanism including coronary vasospasm and microvascular dysfunction and is not a benign condition. Compared to asymptomatic individuals, INOCA is associated with increased incidence of cardiovascular events, repeated hospital admissions, as well as impaired quality of life and associated increased health care costs. This consensus document provides a definition of INOCA and guidance to the community on the diagnostic approach and management of INOCA based on existing evidence from research and best available clinical practice; noting gaps in knowledge and potential areas for further investigation.
Identifiants
pubmed: 32626906
pii: 5867624
doi: 10.1093/eurheartj/ehaa503
pmc: PMC7577516
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3504-3520Subventions
Organisme : British Heart Foundation
ID : RE/18/6134217
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S005714/1
Pays : United Kingdom
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Organisme : British Heart Foundation
ID : PG/17/2532884
Pays : United Kingdom
Organisme : British Heart Foundation
ID : FS/17/26/32744
Pays : United Kingdom
Organisme : British Heart Foundation
ID : CS/15/7/31679
Pays : United Kingdom
Informations de copyright
The article has been co-published with permission in the European Heart Journal and EuroIntervention. All rights reserved. © 2020 the Author(s). These articles are identical except for minor stylistic and spelling differences in keeping with each journal's style. Either citation can be used when citing this article.
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