Neurolymphomatosis, a rare manifestation of peripheral nerve involvement in lymphomas: Suggestive features and diagnostic challenges.


Journal

Journal of the peripheral nervous system : JPNS
ISSN: 1529-8027
Titre abrégé: J Peripher Nerv Syst
Pays: United States
ID NLM: 9704532

Informations de publication

Date de publication:
09 2020
Historique:
received: 15 06 2020
revised: 29 06 2020
accepted: 30 06 2020
pubmed: 7 7 2020
medline: 21 9 2021
entrez: 7 7 2020
Statut: ppublish

Résumé

Neurolymphomatosis, the infiltration of the peripheral nervous system from lymphoid cells, represents an uncommon manifestation of lymphomas. We describe the challenging diagnostic work-up in a patient with neurolymphomatosis. A 58-year-old woman with previous breast diffuse large B-cell lymphoma treated with chemo- and radiation-therapy, presented with dysesthesias, neuropathic pain at left abdomen and thigh, and weakness at left lower limb 9 years after disease remission. Neurophysiology revealed left T10-L4 radiculo-plexopathy with no abnormalities at cerebrospinal fluid (CSF), nerve ultrasound, and

Identifiants

pubmed: 32627254
doi: 10.1111/jns.12401
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

312-315

Informations de copyright

© 2020 Peripheral Nerve Society.

Références

Briani C, Visentin A, Campagnolo M, et al. Peripheral nervous system involvement in lymphomas. J Peripheral Ner Syst. 2019;24:5-18.
Briani C, Vitaliani R, Grisold W, et al. Spectrum of paraneoplastic disease associated with lymphoma. Neurology. 2011;76:705-710.
Gasparotti R, Lucchetta M, Cacciavillani M, et al. Neuroimaging in diagnosis of atypical polyradiculoneuropathies: report of three cases and review of the literature. J Neurol. 2015;262:1714-1723.
Baehring JM, Batchelor TT. Diagnosis and management of neurolymphomatosis. Cancer J. 2012;18:463-468.
Tomita M, Koike H, Kawagashira Y, et al. Clinicopathological features of neuropathy associated with lymphoma. Brain. 2013;136:2563-2578.

Auteurs

Marta Campagnolo (M)

Neurology Unit, Department of Neurosciences, University of Padova, Padova, Italy.

Mario Cacciavillani (M)

EMG Lab, CEMES, Synlab Group, Padova, Italy.

Tiziana Cavallaro (T)

Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.

Sergio Ferrari (S)

Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.

Roberto Gasparotti (R)

Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.

Renato Zambello (R)

Hematology and Clinical Immunology Unit, Department of Medicine, University of Padova, Padova, Italy.

Chiara Briani (C)

Neurology Unit, Department of Neurosciences, University of Padova, Padova, Italy.

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Classifications MeSH