World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia.
Alzheimer's disease
World-Wide FINGERS
cognitive impairment
dementia
lifestyle
multidomain intervention
prevention
randomized controlled trial
Journal
Alzheimer's & dementia : the journal of the Alzheimer's Association
ISSN: 1552-5279
Titre abrégé: Alzheimers Dement
Pays: United States
ID NLM: 101231978
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
23
08
2019
revised:
11
03
2020
accepted:
30
04
2020
pubmed:
7
7
2020
medline:
2
6
2021
entrez:
7
7
2020
Statut:
ppublish
Résumé
Reducing the risk of dementia can halt the worldwide increase of affected people. The multifactorial and heterogeneous nature of late-onset dementia, including Alzheimer's disease (AD), indicates a potential impact of multidomain lifestyle interventions on risk reduction. The positive results of the landmark multidomain Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) support such an approach. The World-Wide FINGERS (WW-FINGERS), launched in 2017 and including over 25 countries, is the first global network of multidomain lifestyle intervention trials for dementia risk reduction and prevention. WW-FINGERS aims to adapt, test, and optimize the FINGER model to reduce risk across the spectrum of cognitive decline-from at-risk asymptomatic states to early symptomatic stages-in different geographical, cultural, and economic settings. WW-FINGERS aims to harmonize and adapt multidomain interventions across various countries and settings, to facilitate data sharing and analysis across studies, and to promote international joint initiatives to identify globally implementable and effective preventive strategies.
Identifiants
pubmed: 32627328
doi: 10.1002/alz.12123
pmc: PMC9527644
mid: NIHMS1804464
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1078-1094Subventions
Organisme : NIA NIH HHS
ID : P30 AG049638
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG062689
Pays : United States
Organisme : Intramural NIH HHS
ID : Z01 AG007420
Pays : United States
Organisme : NIH HHS
ID : R01AG062689
Pays : United States
Organisme : World Health Organization
ID : 001
Pays : International
Organisme : CIHR
ID : 201901CNA‐417847‐CAN‐ABPI‐ 32054
Pays : Canada
Informations de copyright
© 2020 The Authors. Alzheimer's & Dementia published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association.
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