[A new antiviral isoquinoline alkaloid from Thalictrum glandulosissimum].

Alkaloids Antiviral Agents Isoquinolines Thalictrum Tobacco Mosaic Virus
Thalictrum glandulosissimum anti-tobacco mosaic virus activity isoquinoline alkaloid

Journal

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
ISSN: 1001-5302
Titre abrégé: Zhongguo Zhong Yao Za Zhi
Pays: China
ID NLM: 8913656

Informations de publication

Date de publication:
Jun 2020
Historique:
entrez: 7 7 2020
pubmed: 7 7 2020
medline: 18 9 2020
Statut: ppublish

Résumé

A new isoquinoline alkaloid(1) has been isolated from the whole plant of Thalictrum glandulosissimum by using various chromatographic techniques, including silica gel, sephadex, MCI-gel resin, and RP-HPLC, and its structure was determined as 1-(6-hydroxy-7-methylisoquinolin-1-yl) ethantone by physicochemical properties and spectroscopic data. This compound was evaluated for anti-tobacco mosaic virus(TMV) activity. The results showed that it had prominent anti-TMV activity with inhibition rates of 28.4%. This rate was closed to that of positive control.

Identifiants

DOI: 10.19540/j.cnki.cjcmm.20200229.203 PMID: 32627490
pubmed: 32627490
doi: 10.19540/j.cnki.cjcmm.20200229.203
doi:

Substances chimiques

Alkaloids 0
Antiviral Agents 0
Isoquinolines 0

Types de publication

Journal Article

Langues

chi

Sous-ensembles de citation

IM

Pagination

2568-2570

Auteurs

Dian Luo (D)

College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Na Lyu (N)

College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Ling-Min Liao (LM)

College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Qian Gao (Q)

Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Yin-Ke Li (YK)

College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Jing Li (J)

Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Xin Liu (X)

Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Xue-Mei Li (XM)

Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Guang-Yu Yang (GY)

College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Yan-Qing Ye (YQ)

College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China.

Qiu-Fen Hu (QF)

College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China Technology Center, China Tobacco Yunnan Industrial Co., Ltd. Kunming 650106, China.

Miao Dong (M)

College of Chinese National Medicine, Yunnan Minzu University Kunming 650500, China.

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Alcaloïdes › [A new antiviral isoquinoline alkaloid from...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › [A new antiviral isoquinoline alkaloid from...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Isoquinoléines › [A new antiviral isoquinoline alkaloid from...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Ranunculales › Ranonculaceae › Thalictrum › [A new antiviral isoquinoline alkaloid from...
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Tobamovirus › Virus de la mosaïque du tabac › [A new antiviral isoquinoline alkaloid from...