Macromolecular crystallography beamlines at the Canadian Light Source: building on success.

Canadian Light Source beamline double crystal/multi-layer monochromator macromolecular crystallography

Journal

Acta crystallographica. Section D, Structural biology
ISSN: 2059-7983
Titre abrégé: Acta Crystallogr D Struct Biol
Pays: United States
ID NLM: 101676043

Informations de publication

Date de publication:
01 Jul 2020
Historique:
received: 09 03 2020
accepted: 04 06 2020
entrez: 7 7 2020
pubmed: 7 7 2020
medline: 14 5 2021
Statut: ppublish

Résumé

The Canadian Macromolecular Crystallography Facility (CMCF) consists of two beamlines dedicated to macromolecular crystallography: CMCF-ID and CMCF-BM. After the first experiments were conducted in 2006, the facility has seen a sharp increase in usage and has produced a significant amount of data for the Canadian crystallographic community. Upgrades aimed at increasing throughput and flux to support the next generation of more demanding experiments are currently under way or have recently been completed. At CMCF-BM, this includes an enhanced monochromator, automounter software upgrades and a much faster detector. CMCF-ID will receive a major upgrade including a new undulator, a new monochromator and new optics to stably focus the beam onto a smaller sample size, as well as a brand-new detector.

Identifiants

pubmed: 32627736
pii: S2059798320007603
doi: 10.1107/S2059798320007603
pmc: PMC7336384
doi:

Substances chimiques

Macromolecular Substances 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

630-635

Informations de copyright

open access.

Références

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Nat Commun. 2019 Sep 24;10(1):4328
pubmed: 31551421
J Synchrotron Radiat. 2011 Jul;18(Pt 4):681-4
pubmed: 21685687
Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6812-6817
pubmed: 30894493
Nat Commun. 2019 Apr 23;10(1):1849
pubmed: 31015395
Cancer Cell. 2019 May 13;35(5):721-737.e9
pubmed: 31056398
J Synchrotron Radiat. 2014 May;21(Pt 3):633-7
pubmed: 24763655
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):125-32
pubmed: 20124692

Auteurs

Michel Fodje (M)

Canadian Macromolecular Crystallography Facility, Canadian Light Source, 44 Innovation Boulevard, Saskatoon, SK S7N 2V3, Canada.

Kiran Mundboth (K)

Canadian Macromolecular Crystallography Facility, Canadian Light Source, 44 Innovation Boulevard, Saskatoon, SK S7N 2V3, Canada.

Shaunivan Labiuk (S)

Canadian Macromolecular Crystallography Facility, Canadian Light Source, 44 Innovation Boulevard, Saskatoon, SK S7N 2V3, Canada.

Kathryn Janzen (K)

Canadian Macromolecular Crystallography Facility, Canadian Light Source, 44 Innovation Boulevard, Saskatoon, SK S7N 2V3, Canada.

James Gorin (J)

Canadian Macromolecular Crystallography Facility, Canadian Light Source, 44 Innovation Boulevard, Saskatoon, SK S7N 2V3, Canada.

Denis Spasyuk (D)

Canadian Macromolecular Crystallography Facility, Canadian Light Source, 44 Innovation Boulevard, Saskatoon, SK S7N 2V3, Canada.

Scott Colville (S)

Canadian Macromolecular Crystallography Facility, Canadian Light Source, 44 Innovation Boulevard, Saskatoon, SK S7N 2V3, Canada.

Pawel Grochulski (P)

Canadian Macromolecular Crystallography Facility, Canadian Light Source, 44 Innovation Boulevard, Saskatoon, SK S7N 2V3, Canada.

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Classifications MeSH