Myocardial blush grade: a determinant of left ventricular ejection fraction and adverse outcomes in STEMI.
Adult
Coronary Angiography
/ methods
Female
Humans
Male
Microcirculation
Middle Aged
Myocardial Perfusion Imaging
/ methods
Percutaneous Coronary Intervention
Postoperative Period
Predictive Value of Tests
Prognosis
Prospective Studies
Regression Analysis
ST Elevation Myocardial Infarction
/ diagnostic imaging
Severity of Illness Index
Stroke Volume
Treatment Outcome
Ventricular Function, Left
Blush grade
PCI
STEMI
TIMI
Journal
Scottish medical journal
ISSN: 0036-9330
Titre abrégé: Scott Med J
Pays: Scotland
ID NLM: 2983335R
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
pubmed:
8
7
2020
medline:
4
9
2021
entrez:
8
7
2020
Statut:
ppublish
Résumé
Despite restoration of blood flow, subtle microvascular obstruction can occur. This obstruction can be graded using myocardial blush grade. We aimed to investigate the role of myocardial blush grade in ejection fraction and adverse outcomes, after percutaneous intervention. A prospective, observational study was conducted at our institute with a calculated sample size. Variables such as age, gender, and ejection fraction were noted before the intervention. The patients were followed for 3 months to determine the outcomes. The data was analyzed using IBM SPSS software version 26.0. P-value of less than 0.05 was considered significant for the statistical tests. There were 74 male and 36 female participants in the study. The mean age was 52.20 ± 10.02 years. The most common adverse outcome was heart failure (18%). There was a significant Pearson's correlation between myocardial blush grade and improvement in ejection fraction (p < 0.05). Improvement in myocardial blush grade was significantly related to a decrease in adverse outcomes (p < 0.05). Regression analysis proved myocardial blush grade and diabetes status as independent predictors of percentage increase in ejection fraction (p < 0.05). High myocardial blush grade is one of the independent predictors of better outcomes in ST-elevation myocardial infarction.
Sections du résumé
BACKGROUND AND AIMS
OBJECTIVE
Despite restoration of blood flow, subtle microvascular obstruction can occur. This obstruction can be graded using myocardial blush grade. We aimed to investigate the role of myocardial blush grade in ejection fraction and adverse outcomes, after percutaneous intervention.
METHODS
METHODS
A prospective, observational study was conducted at our institute with a calculated sample size. Variables such as age, gender, and ejection fraction were noted before the intervention. The patients were followed for 3 months to determine the outcomes. The data was analyzed using IBM SPSS software version 26.0. P-value of less than 0.05 was considered significant for the statistical tests.
RESULTS
RESULTS
There were 74 male and 36 female participants in the study. The mean age was 52.20 ± 10.02 years. The most common adverse outcome was heart failure (18%). There was a significant Pearson's correlation between myocardial blush grade and improvement in ejection fraction (p < 0.05). Improvement in myocardial blush grade was significantly related to a decrease in adverse outcomes (p < 0.05). Regression analysis proved myocardial blush grade and diabetes status as independent predictors of percentage increase in ejection fraction (p < 0.05).
CONCLUSION
CONCLUSIONS
High myocardial blush grade is one of the independent predictors of better outcomes in ST-elevation myocardial infarction.
Identifiants
pubmed: 32631149
doi: 10.1177/0036933020941260
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM