Epidemiological and clinical characteristics of a familial cluster of COVID-19.
Adult
Aged, 80 and over
Asymptomatic Infections
Betacoronavirus
COVID-19
COVID-19 Testing
China
Clinical Laboratory Techniques
Coronavirus Infections
/ diagnosis
Family Health
Female
Humans
Leukocyte Count
Lung
/ diagnostic imaging
Middle Aged
Pandemics
Pneumonia, Viral
/ diagnosis
Retrospective Studies
SARS-CoV-2
Tomography, X-Ray Computed
Travel
Asymptomatic transmission
Outside Wuhan
coronavirus disease 2019
transmission and clinical characteristics
Journal
Epidemiology and infection
ISSN: 1469-4409
Titre abrégé: Epidemiol Infect
Pays: England
ID NLM: 8703737
Informations de publication
Date de publication:
07 07 2020
07 07 2020
Historique:
pubmed:
8
7
2020
medline:
22
7
2020
entrez:
8
7
2020
Statut:
epublish
Résumé
We report a family cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection involving five patients in a family cluster in Dazhou, China, including the epidemiological, clinical, laboratory and radiological findings. Three-generation transmission was observed. Through epidemiological investigation, we observed asymptomatic transmission to a cohabiting family member, as well as person-to-person transmission of SARS-CoV-2 outside Wuhan city. The asymptomatic transmission demonstrated here provides evidence that there could be a greater risk of Coronavirus Disease 2019 (COVID-19) spread. This cluster also demonstrated that COVID-19 is transmissible during the incubation period of an asymptomatic person. Early isolation and treatment, stressing prevention of cluster outbreaks, could help prevent further spread of the epidemic.
Identifiants
pubmed: 32631470
doi: 10.1017/S0950268820001521
pii: S0950268820001521
pmc: PMC7369338
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e145Références
Lancet. 2020 Feb 15;395(10223):514-523
pubmed: 31986261
Eur J Nucl Med Mol Imaging. 2020 May;47(5):1275-1280
pubmed: 32107577
Clin Infect Dis. 2020 Mar 16;:
pubmed: 32176772
BMJ. 2020 Feb 19;368:m606
pubmed: 32075786
J Clin Med. 2020 Feb 20;9(2):
pubmed: 32093211
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Lancet. 2020 Feb 15;395(10223):507-513
pubmed: 32007143
MMWR Morb Mortal Wkly Rep. 2020 Mar 27;69(12):343-346
pubmed: 32214079
Euro Surveill. 2020 Mar;25(10):
pubmed: 32183930
Epidemiol Health. 2020;42:e2020007
pubmed: 32035431
N Engl J Med. 2020 Mar 26;382(13):1199-1207
pubmed: 31995857
J Infect. 2020 Jul;81(1):e102-e103
pubmed: 32335174
Indian J Pediatr. 2020 Apr;87(4):281-286
pubmed: 32166607
N Engl J Med. 2020 Feb 27;382(9):872-874
pubmed: 31991079
JAMA. 2020 Feb 7;:
pubmed: 32031568
Microbes Infect. 2020 May - Jun;22(4-5):212-217
pubmed: 32387682
N Engl J Med. 2020 Mar 19;382(12):1177-1179
pubmed: 32074444
JAMA. 2020 Feb 7;:
pubmed: 32031570
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Feb 10;41(2):139-144
pubmed: 32057211
J Med Virol. 2020 May;92(5):518-521
pubmed: 32022275
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Feb 10;41(2):145-151
pubmed: 32064853