Cancer and Systemic Lupus Erythematosus.

Humans Lupus Erythematosus, Systemic / complications Neoplasms / epidemiology
Cancer Epidemiology Malignancy Systemic lupus erythematosus

Journal

Rheumatic diseases clinics of North America
ISSN: 1558-3163
Titre abrégé: Rheum Dis Clin North Am
Pays: United States
ID NLM: 8708093

Informations de publication

Date de publication:
Aug 2020
Historique:
entrez: 8 7 2020
pubmed: 8 7 2020
medline: 26 8 2021
Statut: ppublish

Résumé

Systemic lupus erythematosus is associated with a small overall increased cancer risk compared with the general population. This risk includes a 4-fold increased risk of non-Hodgkin lymphoma, but a decreased risk of other cancers (such as breast cancer). The pathophysiology underlying the increased risk of hematologic cancer is not fully understood, but many potential mechanisms have been proposed, including dysfunction of the tumor necrosis factor and other pathways. A decreased risk of breast, ovarian, and endometrial cancer might be driven by hormonal factors or lupus-related antibodies, but these links have not been proved.

Identifiants

DOI: 10.1016/j.rdc.2020.05.005 PMID: 32631602
pubmed: 32631602
pii: S0889-857X(20)30057-0
doi: 10.1016/j.rdc.2020.05.005
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

533-550

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure None.

Auteurs

Alexandra Ladouceur (A)

Department of Medicine, McGill University, 1001 Decarie Boulevard, Suite D05-2212, Montreal, Quebec H4A 3J1, Canada.

Basile Tessier-Cloutier (B)

Department of Pathology and Laboratory Medicine, University of British Columbia, Room G227 - 2211 Wesbrook Mall, Vancouver, British Columbia V6T 2B5, Canada.

Ann E Clarke (AE)

Division of Rheumatology, University of Calgary, 3330 Hospital Drive Northwest, Calgary, Alberta T2N 4N1, Canada.

Rosalind Ramsey-Goldman (R)

Division of Rheumatology, Northwestern University Feinberg School of Medicine, McGaw Pavilion, 240 East Huron Street, Suite M-300, Chicago, IL 60611, USA.

Caroline Gordon (C)

Rheumatology Research Group, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.

James E Hansen (JE)

Department of Therapeutic Radiology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.

Sasha Bernatsky (S)

Department of Medicine, McGill University, 1001 Decarie Boulevard, Suite D05-2212, Montreal, Quebec H4A 3J1, Canada; Division of Clinical Epidemiology, Research Institute of McGill University Health Centre, 5252 de Maisonneuve West, 3rd Floor, Montreal, Quebec H4A 3S5, Canada. Electronic address: sasha.bernatsky@mcgill.ca.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Cancer and Systemic Lupus Erythematosus.
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Lupus érythémateux disséminé › Cancer and Systemic Lupus Erythematosus.
questionsmedicales.fr › Tumeurs › Cancer and Systemic Lupus Erythematosus.