A data-based mathematical modelling study to quantify the effects of ciprofloxacin and ampicillin on the within-host dynamics of


Journal

Journal of the Royal Society, Interface
ISSN: 1742-5662
Titre abrégé: J R Soc Interface
Pays: England
ID NLM: 101217269

Informations de publication

Date de publication:
07 2020
Historique:
entrez: 8 7 2020
pubmed: 8 7 2020
medline: 22 6 2021
Statut: ppublish

Résumé

Antibiotic therapy has drastically reduced the mortality and sequelae of bacterial infections. From naturally occurring to chemically synthesized, different classes of antibiotics have been successfully used without detailed knowledge of how they affect bacterial dynamics

Identifiants

pubmed: 32634369
doi: 10.1098/rsif.2020.0299
pmc: PMC7423434
doi:

Substances chimiques

Anti-Bacterial Agents 0
Ciprofloxacin 5E8K9I0O4U
Ampicillin 7C782967RD

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

20200299

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M020193
Pays : United Kingdom

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Auteurs

Myrto Vlazaki (M)

Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

Omar Rossi (O)

GSK Vaccines Institute for Global Health, Via Fiorentina 1, 53100 Siena, Italy.

David J Price (DJ)

Centre of Epidemiology and Biostatistics, University of Melbourne, Grattan Street, Parkville, Victoria 3010, Australia.
The Doherty Institute for Infection and Immunity, 792 Elizabeth Street, Melbourne, Victoria 3000, Australia.

Callum McLean (C)

Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

Andrew J Grant (AJ)

Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

Pietro Mastroeni (P)

Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

Olivier Restif (O)

Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

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Classifications MeSH