Periodontal Disease and Periodontal Disease-Related Bacteria Involved in the Pathogenesis of Alzheimer's Disease.
Porphylomonas gingivalis
amyloid β
blood-brain barrier
cognitive decline
vascular inflammation
Journal
Journal of inflammation research
ISSN: 1178-7031
Titre abrégé: J Inflamm Res
Pays: New Zealand
ID NLM: 101512684
Informations de publication
Date de publication:
2020
2020
Historique:
received:
02
04
2020
accepted:
29
05
2020
entrez:
9
7
2020
pubmed:
9
7
2020
medline:
9
7
2020
Statut:
epublish
Résumé
Alzheimer's disease (AD) is the most common cause of dementia, and it exhibits pathological properties such as deposition of extracellular amyloid β (Aβ) and abnormally phosphorylated Tau in nerve cells and a decrease of synapses. Conventionally, drugs targeting Aβ and its related molecules have been developed on the basis of the amyloid cascade hypothesis, but sufficient effects on the disease have not been obtained in past clinical trials. On the other hand, it has been pointed out that chronic inflammation and microbial infection in the brain may be involved in the pathogenesis of AD. Recently, attention has been focused on the relationship between the periodontopathic bacterium
Identifiants
pubmed: 32636667
doi: 10.2147/JIR.S255309
pii: 255309
pmc: PMC7335281
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
275-283Informations de copyright
© 2020 Matsushita et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
Références
Cell Microbiol. 2012 Jul;14(7):1085-96
pubmed: 22381126
J Periodontol. 2003 Jan;74(1):111-8
pubmed: 12593605
Infect Immun. 2005 Mar;73(3):1543-52
pubmed: 15731052
Brain Res. 2001 Mar 30;896(1-2):36-42
pubmed: 11277970
J Clin Periodontol. 2006 Jun;33(6):401-7
pubmed: 16677328
Circ J. 2015;79(9):1882-90
pubmed: 26212124
Neurology. 2009 Sep 8;73(10):768-74
pubmed: 19738171
Sci Rep. 2015 Oct 15;5:15015
pubmed: 26468932
Sci Rep. 2017 Oct 19;7(1):13537
pubmed: 29051531
Periodontol 2000. 2010 Oct;54(1):15-44
pubmed: 20712631
J Nutr Biochem. 2019 Jan;63:101-108
pubmed: 30366260
Nat Commun. 2017 Jun 20;8(1):24
pubmed: 28634323
Neurobiol Aging. 2007 Apr;28(4):533-6
pubmed: 16569464
Neurobiol Aging. 2000 May-Jun;21(3):383-421
pubmed: 10858586
Neurology. 2008 Apr 1;70(14):1222-3; author reply 1223
pubmed: 18378889
Alzheimers Dement. 2008 Jul;4(4):242-50
pubmed: 18631974
BMC Psychiatry. 2018 Oct 20;18(1):345
pubmed: 30342524
Alzheimers Res Ther. 2017 Aug 8;9(1):56
pubmed: 28784164
Can J Physiol Pharmacol. 2006 Jan;84(1):49-59
pubmed: 16845890
Science. 2013 Jan 11;339(6116):156-61
pubmed: 23307732
Nat Rev Endocrinol. 2011 Jun 28;7(12):738-48
pubmed: 21709707
Lancet Neurol. 2016 Aug;15(9):934-943
pubmed: 27312738
J Atheroscler Thromb. 2016 Aug 1;23(8):908-21
pubmed: 26947598
J Alzheimers Dis. 2009;16(4):677-85
pubmed: 19387104
Neurobiol Aging. 1995 May-Jun;16(3):271-8; discussion 278-84
pubmed: 7566337
Neuropharmacology. 2015 Sep;96(Pt A):29-41
pubmed: 25445485
Science. 2002 Jul 19;297(5580):353-6
pubmed: 12130773
Glia. 2002 Nov;40(2):140-55
pubmed: 12379902
Mol Oral Microbiol. 2016 Oct;31(5):365-78
pubmed: 26466922
Mol Pharm. 2012 Apr 2;9(4):708-17
pubmed: 22081976
Brain. 2015 May;138(Pt 5):1138-59
pubmed: 25823474
Front Genet. 2018 Sep 10;9:362
pubmed: 30250480
Front Neurol. 2018 Nov 12;9:926
pubmed: 30483207
Curr Alzheimer Res. 2011 Aug;8(5):510-9
pubmed: 21605048
Neurobiol Aging. 2013 Dec;34(12):2715-25
pubmed: 23831373
Protein Cell. 2017 Feb;8(2):90-102
pubmed: 27866330
Infect Immun. 2012 Jul;80(7):2570-6
pubmed: 22508864
Cochrane Database Syst Rev. 2006 Apr 19;(2):CD003154
pubmed: 16625572
Mediators Inflamm. 2015;2015:137357
pubmed: 26063967
Nutr Rev. 2016 Oct;74(10):624-34
pubmed: 27634977
Curr Neuropharmacol. 2018;16(7):1059-1085
pubmed: 29046155
Glia. 2007 Oct;55(13):1362-73
pubmed: 17654704
Sci Rep. 2019 Jan 30;9(1):1008
pubmed: 30700769
JDR Clin Trans Res. 2016 Apr;1(1):10-19
pubmed: 30931697
Cochrane Database Syst Rev. 2006 Jan 25;(1):CD005593
pubmed: 16437532
Biol Psychiatry. 2015 Jan 1;77(1):43-51
pubmed: 24951455
Cell. 2014 Jul 3;158(1):15-24
pubmed: 24995975
Lancet Neurol. 2015 Apr;14(4):388-405
pubmed: 25792098
Arch Oral Biol. 2019 Jun;102:225-230
pubmed: 31079020
Neurobiol Aging. 2017 Jan;49:60-68
pubmed: 27776263
J Vasc Surg. 2005 Jul;42(1):107-15
pubmed: 16012459
Brain. 2013 Sep;136(Pt 9):2697-706
pubmed: 23842566
Sci Adv. 2019 Jan 23;5(1):eaau3333
pubmed: 30746447
J Neuroinflammation. 2015 Mar 04;12:42
pubmed: 25889879
Curr Opin Pharmacol. 2017 Dec;37:87-92
pubmed: 29107872
Atherosclerosis. 2007 Jul;193(1):222-8
pubmed: 16872615
Neurobiol Aging. 2014 Sep;35 Suppl 2:S59-64
pubmed: 24970568
Biol Psychiatry. 2008 Sep 15;64(6):484-90
pubmed: 18514163
Nat Rev Neurol. 2010 Apr;6(4):193-201
pubmed: 20234358
J Alzheimers Dis. 2013;36(4):665-77
pubmed: 23666172
J Neurol Neurosurg Psychiatry. 2015 Dec;86(12):1299-306
pubmed: 26294005
Neurology. 1996 Aug;47(2):425-32
pubmed: 8757015
Alzheimers Res Ther. 2015 Aug 19;7(1):56
pubmed: 26286145
Int J Neurosci. 2014 May;124(5):307-21
pubmed: 23930978
PLoS One. 2016 Mar 10;11(3):e0151081
pubmed: 26963387
Circulation. 2008 Jun 17;117(24):3118-25
pubmed: 18541739
J Neurosci Res. 1995 Aug 15;41(6):717-26
pubmed: 7500373
Mol Neurodegener. 2018 Dec 12;13(1):64
pubmed: 30541602
Sci Rep. 2019 Dec 18;9(1):19227
pubmed: 31852995
Infect Immun. 2003 Aug;71(8):4742-8
pubmed: 12874356
J Alzheimers Dis. 2017;58(1):1-15
pubmed: 28372330
Arch Neurol. 2004 May;61(5):668-72
pubmed: 15148142
Periodontol 2000. 2013 Jun;62(1):271-86
pubmed: 23574472
Nutrients. 2019 Mar 13;11(3):
pubmed: 30871219
J Periodontol. 2009 Sep;80(9):1511-7
pubmed: 19722803
Stroke. 2004 Feb;35(2):496-501
pubmed: 14707235
J Alzheimers Dis. 2014;41(1):301-11
pubmed: 24614898
NPJ Aging Mech Dis. 2017 Nov 6;3:15
pubmed: 29134111
PLoS One. 2010 Mar 03;5(3):e9505
pubmed: 20209079
Neuron. 2012 May 24;74(4):691-705
pubmed: 22632727
Alzheimers Dement. 2011 May;7(3):280-92
pubmed: 21514248
BMC Microbiol. 2014 Sep 03;14:229
pubmed: 25179218
J Oral Microbiol. 2016 Nov 22;8:33029
pubmed: 27882863
J Alzheimers Dis. 2016;51(4):979-84
pubmed: 26967229