The epidemiological characterization and geographic distribution of hepatitis D virus infection in Libya.
Adolescent
Adult
Age Factors
Child
Child, Preschool
Coinfection
Female
HIV Infections
/ epidemiology
Hepatitis B Surface Antigens
/ immunology
Hepatitis C
/ epidemiology
Hepatitis D
/ epidemiology
Humans
Infant
Libya
/ epidemiology
Male
Middle Aged
Prevalence
Risk Factors
Substance Abuse, Intravenous
/ epidemiology
Young Adult
Libya
hepatitis D virus
risk factors
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2020
2020
Historique:
received:
12
08
2019
accepted:
03
03
2020
entrez:
9
7
2020
pubmed:
9
7
2020
medline:
29
12
2020
Statut:
epublish
Résumé
North Africa is known to be endemic for hepatitis D virus. However, data one the prevalence of this virus in Libya are scanty. This study aimed to determine the prevalence of hepatitis D virus infection in Libya and analyze the demographic factors associated with the infection, and also to assess the variations across the regions and districts. A total of 1873 samples collected from all over the country were tested for antibodies against hepatitis B surface antigen and the results were correlated with demographic and geographic variables. The overall prevalence of hepatitis D virus infection was 1.7%. The prevalence rate was significantly high among those aged over 40 years (P < 0.001) and it was associated with intravenous drug use and coinfection with human immunodeficiency virus and/or hepatitis C virus infection (P < 0.001). The prevalence rates varied with geographic location and differed markedly within the regions the country. The highest rate reported was in the central region of Libya, followed by the western and eastern regions. Hepatitis D virus infection rate in Libya is considered to be low but is of some concern in some districts. This has been propagated by population displacement and African immigrants, indicating that a continuous epidemiological surveillance program should be implemented.
Identifiants
pubmed: 32637018
doi: 10.11604/pamj.2020.35.120.20055
pii: PAMJ-35-120
pmc: PMC7320781
doi:
Substances chimiques
Hepatitis B Surface Antigens
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
120Informations de copyright
© Mohamed Ali Daw et al.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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