A Systematic Review of the Prevalence and Diagnostic Workup of PIK3CA Mutations in HR+/HER2- Metastatic Breast Cancer.
Journal
International journal of breast cancer
ISSN: 2090-3170
Titre abrégé: Int J Breast Cancer
Pays: Egypt
ID NLM: 101568103
Informations de publication
Date de publication:
2020
2020
Historique:
received:
21
10
2019
accepted:
28
04
2020
entrez:
9
7
2020
pubmed:
9
7
2020
medline:
9
7
2020
Statut:
epublish
Résumé
PIK3CA mutation frequency varies among breast cancer (BC) subtypes. Recent evidence suggests combination therapy with the PI3K inhibitor (PI3Ki) alpelisib and endocrine therapy (ET) improves response rates and progression-free survival (PFS) in
Identifiants
pubmed: 32637176
doi: 10.1155/2020/3759179
pmc: PMC7322582
doi:
Types de publication
Journal Article
Langues
eng
Pagination
3759179Informations de copyright
Copyright © 2020 Elizabeth J. Anderson et al.
Déclaration de conflit d'intérêts
The authors declare that this study received funding from Novartis. The funder had the following involvement with the study: study design, writing of the article, and the decision to submit for publication. EJA, LM, and JD received research funds from Novartis to support this study. EP is an employee of Novartis. At the time of the study, DT was an employee of Novartis. AA receives research funding from Varian Medical Systems unrelated to the current project. LD and TW have no conflicts to disclose.
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