CT Role in the Assessment of Existence of Breast Cancerous Cells.
Blood
Body Fluids
HU Measurements
Tomography, X-Ray Computed
Journal
Journal of biomedical physics & engineering
ISSN: 2251-7200
Titre abrégé: J Biomed Phys Eng
Pays: Iran
ID NLM: 101589641
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
26
05
2015
accepted:
19
06
2015
entrez:
9
7
2020
pubmed:
9
7
2020
medline:
9
7
2020
Statut:
epublish
Résumé
Application of CT- scanning image information and radiation physical characteristics of the biomaterials are two measurable assays for presenting modified cells. This study presented that CT number (HU) and linear attenuation coefficient contain useful information which can be determined during usual CT scanning for the prediction of breast cancerous cells existence based on hemoglobin concentration. This experimental study used breast phantom containing major and minor vessels with diameters of 10 and 5 mm, respectively. The major vessels are filled by water, fat, hemoglobin (Hb) as a normal and 4× concentration of hemoglobin (4×Hb) as a cancerous breast cells, then scanned by single slice CT (GE, Hi Speed) 120 kVp, 100 mA for the determination of linear attenuation coefficient ( The CT numbers were for water (-7 to +7 HU), Hb (22±6 HU) and 4×Hb (80±4 HU). The difference between Hb and 4×Hb was significant ( The study of CT number and linear attenuation coefficient of different concentration of Hb provides a possibility for early predicting of breast cancerous cells existence (4×Hb).
Sections du résumé
BACKGROUND
BACKGROUND
Application of CT- scanning image information and radiation physical characteristics of the biomaterials are two measurable assays for presenting modified cells.
OBJECTIVE
OBJECTIVE
This study presented that CT number (HU) and linear attenuation coefficient contain useful information which can be determined during usual CT scanning for the prediction of breast cancerous cells existence based on hemoglobin concentration.
MATERIAL AND METHODS
METHODS
This experimental study used breast phantom containing major and minor vessels with diameters of 10 and 5 mm, respectively. The major vessels are filled by water, fat, hemoglobin (Hb) as a normal and 4× concentration of hemoglobin (4×Hb) as a cancerous breast cells, then scanned by single slice CT (GE, Hi Speed) 120 kVp, 100 mA for the determination of linear attenuation coefficient (
RESULTS
RESULTS
The CT numbers were for water (-7 to +7 HU), Hb (22±6 HU) and 4×Hb (80±4 HU). The difference between Hb and 4×Hb was significant (
CONCLUSION
CONCLUSIONS
The study of CT number and linear attenuation coefficient of different concentration of Hb provides a possibility for early predicting of breast cancerous cells existence (4×Hb).
Identifiants
pubmed: 32637379
doi: 10.31661/jbpe.v0i0.384
pii: JBPE-10-3
pmc: PMC7321400
doi:
Types de publication
Journal Article
Langues
eng
Pagination
349-356Informations de copyright
Copyright: © Journal of Biomedical Physics and Engineering.
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