Comparisons of pregnancy outcomes between twin pregnancies with and without second-trimester amniocentesis.
Abortion, Spontaneous
/ epidemiology
Adult
Amniocentesis
/ adverse effects
Case-Control Studies
Cohort Studies
Female
Humans
Pregnancy
Pregnancy Outcome
/ epidemiology
Pregnancy Trimester, Second
Pregnancy, Twin
/ statistics & numerical data
Premature Birth
/ epidemiology
Retrospective Studies
Risk Factors
Thailand
/ epidemiology
Journal
Prenatal diagnosis
ISSN: 1097-0223
Titre abrégé: Prenat Diagn
Pays: England
ID NLM: 8106540
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
15
04
2020
revised:
02
07
2020
accepted:
05
07
2020
pubmed:
9
7
2020
medline:
10
11
2021
entrez:
9
7
2020
Statut:
ppublish
Résumé
To assess the amniocentesis-related pregnancy loss rate and preterm birth rate among twin pregnancies undergoing amniocentesis. A retrospective cohort study was conducted at a tertiary center. The study group included twin pregnancies undergoing amniocentesis during 16 to 22 weeks of gestation. The control group was those not undergoing amniocentesis. All amniocenteses were performed by the MFM specialists. The main outcomes were the rate of pregnancy loss (before 24 weeks) and preterm birth. A total of 332 cases in the study group and 1188 controls were analyzed. The percentages of maternal age ≥35 years, high parity, and cases complicated with medical diseases were significantly higher in the study group. The pregnancy loss rate after the procedure tended to be higher, but not significant, in the study group (3.0% vs 2.2% P = .383). Likewise, the rate of preterm birth in the study group was higher, but not significant (70.5% vs 66.0% P = .130). Logistic regression analysis to adjust confounding factors showed no significance of amniocentesis on pregnancy loss and preterm birth. Though amniocentesis in twin pregnancies has theoretical risk of pregnancy loss, it is relatively safe when performed by maternal-fetal medicine specialists. This information is useful for counseling, especially when performed by experienced hands.
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1330-1337Informations de copyright
© 2020 John Wiley & Sons Ltd.
Références
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