Transient receptor potential V1 (TRPV1) modulates the therapeutic effects for comorbidity of pain and depression: The common molecular implication for electroacupuncture and omega-3 polyunsaturated fatty acids.
Amygdala
Chronic pain
Depression
Inflammation
Prefrontal cortex
TRPV1
Journal
Brain, behavior, and immunity
ISSN: 1090-2139
Titre abrégé: Brain Behav Immun
Pays: Netherlands
ID NLM: 8800478
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
21
05
2020
revised:
22
06
2020
accepted:
30
06
2020
pubmed:
9
7
2020
medline:
28
4
2021
entrez:
9
7
2020
Statut:
ppublish
Résumé
Chronic pain and depression are conditions that are highly comorbid and present with overlapping clinical presentations and common pathological biological pathways in neuroinflammation, both of which can be reversed by the use of electroacupuncture (EA) and omega-3 polyunsaturated fatty acids (PUFAs). Transient receptor potential V1 (TRPV1), a Ca
Identifiants
pubmed: 32640285
pii: S0889-1591(20)31033-3
doi: 10.1016/j.bbi.2020.06.033
pii:
doi:
Substances chimiques
Fatty Acids, Omega-3
0
TRPV Cation Channels
0
TRPV1 protein, mouse
0
Docosahexaenoic Acids
25167-62-8
Eicosapentaenoic Acid
AAN7QOV9EA
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
604-614Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.