Correlation between monocyte chemoattractant protein-1/chemokine (C-C motif) ligand 2 and coronary plaque characteristics.
CCL2
Monocyte chemoattractant protein-1
coronary artery disease
intravenous ultrasound
vulnerable plaques
Journal
Experimental biology and medicine (Maywood, N.J.)
ISSN: 1535-3699
Titre abrégé: Exp Biol Med (Maywood)
Pays: England
ID NLM: 100973463
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
pubmed:
10
7
2020
medline:
3
3
2021
entrez:
10
7
2020
Statut:
ppublish
Résumé
Vulnerable plaques are plaques which are susceptible to rupture or thrombosis and trigger a series of adverse events such as coronary disorders. CCL2 is a soluble basic protein belonging to the CC subfamily. Previous studies have been investigated on the correlation between inflammatory factors and clinical events, but there are few studies on the correlation between CCL2 and plaque characteristics. Our study found that the high expression of CCL2 is involved in multiple processes in the genesis and progression of coronary artery disease, and would be a potential clinical prognostic indicator. In addition, high expression of CCL2 may be related to gene pathways such as Nod-like receptor signaling pathway, suggesting that CCL2 is involved in the inflammatory response and immune process of coronary artery disease.
Identifiants
pubmed: 32640896
doi: 10.1177/1535370220941424
pmc: PMC7441351
doi:
Substances chimiques
Chemokine CCL2
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1335-1343Références
PLoS One. 2012;7(3):e33497
pubmed: 22428064
Circulation. 2003 Oct 14;108(15):1772-8
pubmed: 14557340
Circ Res. 2014 Jun 6;114(12):1867-79
pubmed: 24902971
OMICS. 2012 May;16(5):284-7
pubmed: 22455463
Ann Rheum Dis. 2017 May;76(5):914-922
pubmed: 27965260
N Engl J Med. 2013 May 23;368(21):2004-13
pubmed: 23697515
J Am Coll Cardiol. 2007 Nov 27;50(22):2117-24
pubmed: 18036447
Ultrasound Med Biol. 2008 Apr;34(4):655-63
pubmed: 18077081
Circulation. 1989 Apr;79(4):733-43
pubmed: 2647318
N Engl J Med. 2011 Jan 20;364(3):226-35
pubmed: 21247313
Immunol Lett. 2015 Oct;167(2):125-30
pubmed: 26277553
Oncotarget. 2017 Dec 21;9(7):7727-7738
pubmed: 29484147
Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19725-30
pubmed: 22106299
Circulation. 2003 Feb 11;107(5):690-5
pubmed: 12578870
Immunity. 2014 Dec 18;41(6):898-908
pubmed: 25526305
Semin Cancer Biol. 2004 Jun;14(3):149-54
pubmed: 15246049
Lipids Health Dis. 2010 Mar 10;9:27
pubmed: 20219094
J Am Coll Cardiol. 2005 Dec 6;46(11):2038-42
pubmed: 16325038
Arterioscler Thromb Vasc Biol. 1999 Jun;19(6):1518-25
pubmed: 10364084
J Am Coll Cardiol. 2001 Aug;38(2):307-14
pubmed: 11499717
Circ J. 2017 Sep 25;81(10):1439-1446
pubmed: 28458377
Arterioscler Thromb Vasc Biol. 2000 May;20(5):1262-75
pubmed: 10807742
Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15545-50
pubmed: 16199517
Cardiovasc Res. 2010 May 1;86(2):211-8
pubmed: 20202975
Circulation. 1997 Feb 4;95(3):684-92
pubmed: 9024158
Circulation. 2002 Oct 22;106(17):2200-6
pubmed: 12390948
Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):15-26
pubmed: 17082488
Catheter Cardiovasc Interv. 2007 Dec 1;70(7):958-65
pubmed: 17621673
Circulation. 2002 May 28;105(21):2487-92
pubmed: 12034654
J Am Coll Cardiol. 2004 Nov 2;44(9):1812-8
pubmed: 15519012
Cardiovasc J Afr. 2012 Jul;23(6):330-5
pubmed: 22836155
PLoS One. 2015 Mar 18;10(3):e0120633
pubmed: 25786118
Am J Cardiol. 2011 Mar 15;107(6):906-11
pubmed: 21247529
Nat Immunol. 2006 Dec;7(12):1250-7
pubmed: 17110941
Am J Cardiol. 2008 Mar 1;101(5):568-72
pubmed: 18308000
PLoS One. 2017 Jan 3;12(1):e0168888
pubmed: 28045930