Acute Renal Failure in Critically Ill COVID-19 Patients With a Focus on the Role of Renal Replacement Therapy: A Review of What We Know So Far.
continuous renal replacement therapy (crrt)
coronavirus disease 2019 (covid-19)
renal failure
severe acute respiratory syndrome coronavirus-2 (sars-cov-2)
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
03 Jun 2020
03 Jun 2020
Historique:
entrez:
10
7
2020
pubmed:
10
7
2020
medline:
10
7
2020
Statut:
epublish
Résumé
Acute renal failure remains a significant concern in all patients with the coronavirus disease 2019 (COVID-19) infection. Management is particularly challenging in critically ill patients requiring intensive care unit (ICU) level of care. Supportive care in the form of accurate volume correction and avoiding nephrotoxic agents are the chief cornerstone of the management of these patients. The pathophysiology of acute renal failure in COVID-19 is multifactorial, with significant contributions from excessive cytokine release. Gaining a better insight into the pathophysiology of renal failure will hopefully help develop more directed treatment options. A considerable number of these patients deteriorate despite adequate supportive care owing to the complexity of the disease and multi-organ involvement. Renal replacement therapy is used for a long time in critically ill septic patients who develop progressive renal failure despite adequate conservative support. Timing and choice of renal replacement therapy in critically ill COVID-19 patients remains an area of future research that may help decrease mortality in this patient population.
Identifiants
pubmed: 32642345
doi: 10.7759/cureus.8429
pmc: PMC7336623
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e8429Informations de copyright
Copyright © 2020, Raza et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
JAMA. 2008 Feb 20;299(7):793-805
pubmed: 18285591
Nephrol Dial Transplant. 2008 Mar;23(3):904-9
pubmed: 18065435
Kidney Int Suppl. 1999 Nov;(72):S79-83
pubmed: 10560812
Indian J Crit Care Med. 2010 Jan;14(1):14-21
pubmed: 20606904
Clin J Am Soc Nephrol. 2007 May;2(3):431-9
pubmed: 17699448
N Engl J Med. 2018 Oct 11;379(15):1431-1442
pubmed: 30304656
Crit Care Med. 2008 Feb;36(2):610-7
pubmed: 18216610
Crit Care Med. 2002 Oct;30(10):2205-11
pubmed: 12394945
Am J Kidney Dis. 1999 Sep;34(3):486-92
pubmed: 10469859
Dev Cell. 2019 Nov 4;51(3):399-413.e7
pubmed: 31689386
Emerg Microbes Infect. 2020 Dec;9(1):991-993
pubmed: 32342724
Am J Kidney Dis. 2014 Jun;63(6):954-67
pubmed: 24434188
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
Blood Purif. 2020;49(1-2):107-113
pubmed: 31434083
J Med Virol. 2020 Apr 24;:
pubmed: 32330305
Nature. 2020 May;581(7809):465-469
pubmed: 32235945
Crit Care Med. 1998 Dec;26(12):1995-2000
pubmed: 9875910
Kidney Int Rep. 2020 Apr 9;:
pubmed: 32292867
Crit Care. 2011;15(1):R72
pubmed: 21352532
Nephrol Dial Transplant. 2003 May;18(5):961-6
pubmed: 12686672
JAMA. 2016 May 24-31;315(20):2190-9
pubmed: 27209269
JAMA. 1995 Jan 11;273(2):117-23
pubmed: 7799491
Curr Drug Targets. 2009 Dec;10(12):1205-11
pubmed: 19715536
Ren Fail. 2003 Sep;25(5):855-62
pubmed: 14575293
Nephrol Dial Transplant. 2009 Feb;24(2):512-8
pubmed: 18854418
JAMA. 2020 Feb 7;:
pubmed: 32031570
Kidney Int. 2020 Jul;98(1):219-227
pubmed: 32327202
Semin Nephrol. 2019 Sep;39(5):505-514
pubmed: 31514914
N Engl J Med. 2016 Jul 14;375(2):122-33
pubmed: 27181456
J Med Virol. 2020 Apr;92(4):418-423
pubmed: 31967327
Kidney Int. 2001 Sep;60(3):1154-63
pubmed: 11532112
Artif Organs. 2003 Sep;27(9):792-801
pubmed: 12940901
Nephrol Dial Transplant. 1996 Feb;11(2):293-9
pubmed: 8700363
Lancet. 2020 Feb 15;395(10223):507-513
pubmed: 32007143
Cell. 2020 Apr 16;181(2):271-280.e8
pubmed: 32142651
Methods Mol Biol. 2015;1282:1-23
pubmed: 25720466
JAMA. 2020 Mar 11;:
pubmed: 32159775
ASAIO J. 2009 May-Jun;55(3):224-6
pubmed: 19282753
Cochrane Database Syst Rev. 2007 Jul 18;(3):CD003773
pubmed: 17636735
Lancet. 2006 Jul 29;368(9533):379-85
pubmed: 16876666