Attention-Deficit/Hyperactivity Disorder Patients May Have Undiagnosed Narcolepsy.
adult adhd
attention deficit hyperactivity disorder (adhd)
cataplexy
excessive daytime sleepiness
narcolepsy
serum ferritin
serum iron
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
04 Jun 2020
04 Jun 2020
Historique:
entrez:
10
7
2020
pubmed:
10
7
2020
medline:
10
7
2020
Statut:
epublish
Résumé
Background Attention-deficit/hyperactivity disorder (ADHD) patients have many comorbidities. Narcoleptic patients have a big prevalence of ADHD (15%-30%). Both groups suffer from similar symptoms and benefit from the same class of medications. As such, narcolepsy could be masked in ADHD patients. Low serum ferritin has been found both in ADHD patients as well as in patients with narcolepsy. Materials & methods We enrolled 26 participants (14 ADHD patients and 12 controls). They answered several questionnaires, and blood samples were obtained from 20 participants. We had clear exclusion criteria. Results Using the Ullanlinna Narcolepsy Scale (UNS), we identified three possible narcolepsy patients within the ADHD group and no suspects in the control group. There was a statistically significant negative correlation between serum iron levels and ADHD symptom severity. No correlation was found measuring serum ferritin levels. Conclusions Narcolepsy may be more common within ADHD patients than in the general population. Some of these patients could benefit from a change in medication. Low serum iron and ferritin levels could be relevant in ADHD pathophysiology. This requires further exploratory research.
Identifiants
pubmed: 32642351
doi: 10.7759/cureus.8436
pmc: PMC7336577
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e8436Informations de copyright
Copyright © 2020, Wilenius et al.
Déclaration de conflit d'intérêts
The authors have declared financial relationships, which are detailed in the next section.
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