The analgesic efficacy of quadratus lumborum block in caesarean delivery: a meta-analysis and trial sequential analysis.


Journal

Journal of anesthesia
ISSN: 1438-8359
Titre abrégé: J Anesth
Pays: Japan
ID NLM: 8905667

Informations de publication

Date de publication:
12 2020
Historique:
received: 17 04 2020
accepted: 27 06 2020
pubmed: 10 7 2020
medline: 2 2 2021
entrez: 10 7 2020
Statut: ppublish

Résumé

Quadratus lumborum block (QLB) has recently gained popularity for postoperative analgesia after cesarean delivery (CD) as it provides both visceral and somato-sensory blockade of the abdomen. Aim of this meta-analysis was to evaluate the analgesic potential of QLB after CD. Electronic database from inception to December 2019 was searched systematically for randomized-controlled trials comparing QLB with injection of inactive solution in women undergoing CD. Primary outcome was consumption of morphine at 24 h. Morphine consumption at 48 h, dynamic and static pain scores at various time intervals were the secondary outcomes studied. Seven trials met the inclusion criteria. Morphine consumption was reduced significantly with QLB in comparison to sham or no block at 24 h (mean difference [MD] - 9.84 mg; 95% confidence interval [CI] - 18.16, - 0.50; p = 0.04; I QLB significantly reduces opioid requirements in CD and may have analgesic effects lasting 24 h.

Identifiants

pubmed: 32642839
doi: 10.1007/s00540-020-02822-7
pii: 10.1007/s00540-020-02822-7
doi:

Substances chimiques

Anesthetics, Local 0
Morphine 76I7G6D29C

Types de publication

Journal Article Meta-Analysis

Langues

eng

Sous-ensembles de citation

IM

Pagination

814-824

Références

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pubmed: 30122981

Auteurs

Narinder P Singh (NP)

Department of Anaesthesia, MM(DU), Mullana, Ambala, India.

Jeetinder K Makkar (JK)

Department of Anaesthesia and Intensive Care, PGIMER, Sector 12, Chandigarh, 160012, India. jeet1516@gmail.com.

Anuradha Borle (A)

Department of Anesthesia, Washington University in Saint Louis, Saint Louis, MO, USA.

David Monks (D)

Department of Anesthesia, Washington University in Saint Louis, Saint Louis, MO, USA.

Basavana Gouda Goudra (BG)

Department of Anesthesia, Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Andres Zorrilla-Vaca (A)

Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, Baltimore, MD, USA.

Preet Mohinder Singh (PM)

Department of Anesthesia, Washington University in Saint Louis, Saint Louis, MO, USA.

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