Golden Anniversary of the Nicotinic Receptor.

Animals Anniversaries and Special Events Bungarotoxins Receptors, Nicotinic Snake Venoms Torpedo

Journal

Neuron
ISSN: 1097-4199
Titre abrégé: Neuron
Pays: United States
ID NLM: 8809320

Informations de publication

Date de publication:
08 07 2020
Historique:
entrez: 10 7 2020
pubmed: 10 7 2020
medline: 26 9 2020
Statut: ppublish

Résumé

The high-resolution structure of the nicotinic acetylcholine receptor from Torpedo electric tissue in association with the snake toxin α-bungarotoxin (Rahman et al., 2020) is presented 50 years after its identification as the first neurotransmitter receptor and ligand-gated ion channel.

Identifiants

DOI: 10.1016/j.neuron.2020.05.026 PMID: 32645305
pubmed: 32645305
pii: S0896-6273(20)30395-0
doi: 10.1016/j.neuron.2020.05.026
pii:
doi:

Substances chimiques

Bungarotoxins 0
Receptors, Nicotinic 0
Snake Venoms 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

14-16

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Interests The author is part of two patents on the possible therapeutic use of nicotine and orthosteric or allosteric modulators of the nicotinic receptor against COVID-19. (See: Changeux, J.P., Amoura, Z., Rey, F., and Miyara, M. (2020). A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications. Comptes Rendus Biologies 343, 1 33–39, https://doi.org/10.5802/crbiol.8.)

Auteurs

Jean-Pierre Changeux (JP)

Department of Neuroscience, CNRS UMR 3571 Institut Pasteur & Collège de France, 75005 Paris, France. Electronic address: changeux@noos.fr.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Golden Anniversary of the Nicotinic Receptor.
questionsmedicales.fr › Administration des services de santé › Organisation et administration › Relations publiques › Commémorations et événements particuliers › Golden Anniversary of the Nicotinic Receptor.
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Venins › Venins de serpent › Venins des élapidés › Bungarotoxines › Golden Anniversary of the Nicotinic Receptor.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs cholinergiques › Récepteurs nicotiniques › Golden Anniversary of the Nicotinic Receptor.
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Venins › Venins de serpent › Golden Anniversary of the Nicotinic Receptor.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Poisson électrique › Torpedo › Golden Anniversary of the Nicotinic Receptor.