Gene expression analysis of autofluorescence margins in leukoplakia and oral carcinoma: A pilot study.
VELscopeTM
autofluorescence
biopsy margins
gene expression profile
oral potentially malignant disorders
oral squamous cell carcinoma
Journal
Oral diseases
ISSN: 1601-0825
Titre abrégé: Oral Dis
Pays: Denmark
ID NLM: 9508565
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
11
03
2020
revised:
18
06
2020
accepted:
20
06
2020
pubmed:
10
7
2020
medline:
15
1
2021
entrez:
10
7
2020
Statut:
ppublish
Résumé
Autofluorescence is considered a useful technique in the early detection of oral mucosal alterations. However, its efficacy to discriminate tumor margins is still under debate. The purpose of this pilot study was to confirm the existence of molecular divergence from the center of a lesion compared to white light and autofluorescence (VELscope Molecular divergence from the center of the lesion to white light and VELscope Irrespective of pathology, the greatest molecular divergence existed between the center of the lesion and both white light and VELscope Despite the limited low number of patients, our data confirm the benefit of combining autofluorescence with conventional oral examination in identifying surgical margins during biopsy procedures for leukoplakia and oral carcinoma.
Types de publication
Journal Article
Langues
eng
Pagination
193-203Informations de copyright
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved.
Références
Awan, K., Morgan, P., & Warnakulasuriya, S. (2011). Evaluation of an autofluorescence based imaging system (VELscope™ ) in the detection of oral potentially malignant disorders and benign keratoses. Oral Oncology, 47(4), 274-277. https://doi.org/10.1016/j.oraloncology.2011.02.001
Bhatia, N., Lalla, Y., Vu, A. N., & Farah, C. S. (2013). Advances in optical adjunctive aids for visualisation and detection of oral malignant and potentially malignant lesions. International Journal of Dentistry, 2013, 1-17. https://doi.org/10.1155/2013/194029
Di Sanzo, M., Aversa, I., Santamaria, G., Gagliardi, M., Panebianco, M., Biamonte, F., … Costanzo, F. (2016). FTH1P3, a novel H-ferritin pseudogene transcriptionally active, is ubiquitously expressed and regulated during cell differentiation. PLoS One, 11(3), e0151359. https://doi.org/10.1371/journal.pone.0151359
El-Naggar, A. K., Chan, J. K. C., Takata, T., Grandis, J. R., & Slootweg, P. J. (2017). The fourth edition of the head and neck World Health Organization blue book: Editors’ perspectives. Human Pathology, 66, 10-12. https://doi.org/10.1016/j.humpath.2017.05.014
Farah, C. S. (2018). Narrow Band Imaging-guided resection of oral cavity cancer decreases local recurrence and increases survival. Oral Diseases, 24(1-2), 89-97. https://doi.org/10.1111/odi.12745
Farah, C. S., Dalley, A. J., Nguyen, P., Batstone, M., Kordbacheh, F., Perry-Keene, J., & Fielding, D. (2016). Improved surgical margin definition by narrow band imaging for resection of oral squamous cell carcinoma: A prospective gene expression profiling study. Head and Neck, 38(6), 832-839. https://doi.org/10.1002/hed.23989
Farah, C. S., & Fox, S. A. (2019). Dysplastic oral leukoplakia is molecularly distinct from leukoplakia without dysplasia. Oral Diseases, 25(7), 1715-1723. https://doi.org/10.1111/odi.13156
Farah, C. S., Fox, S. A., & Dalley, J. (2018). Integrated miRNA-mRNA spatial signature for oral squamous cell carcinoma: A prospective profiling study of Narrow Band Imaging guided resection. Scientific Reports, 8(1), 823. https://doi.org/10.1038/s41598-018-19341-x
Farah, C. S., Kordbacheh, F., John, K., Bennett, N., & Fox, S. A. (2017). Molecular classification of autofluorescence excision margins in oral potentially malignant disorders. Oral Diseases, 24(5), 732-740. https://doi.org/10.1111/odi.12818
Farah, C. S., & McCullough, M. J. (2008). Oral cancer awareness for the general practitioner: New approaches to patient care. Australian Dental Journal, 53(1), 2-10. https://doi.org/10.1111/j.1834-7819.2007.00002.x
Farah, C. S., Mcintosh, L., Georgiou, A., & Mccullough, M. J. (2012). Efficacy of tissue autofluorescence imaging (VELscope™) in the visualization of oral mucosal lesions. Head and Neck, 34(6), 856-862. https://doi.org/10.1002/hed.21834
Giudice, A., Bennardo, F., Barone, S., Antonelli, A., Figliuzzi, M. M., & Fortunato, L. (2018). Can Autofluorescence guide surgeons in the treatment of medication-related osteonecrosis of the jaw? A prospective feasibility study. Journal of Oral and Maxillofacial Surgery, 76(5), 982-995. https://doi.org/10.1016/j.joms.2017.10.024
Hsu, P. J., Yan, K., Shi, H., Izumchenko, E., & Agrawal, N. (2020). Molecular biology of oral cavity squamous cell carcinoma. Oral Oncology, 102, 104552. https://doi.org/10.1016/j.oraloncology.2019.104552
Ishikawa, S., Sugimoto, M., Edamatsu, K., Sugano, A., Kitabatake, K., & Iino, M. (2020). Discrimination of oral squamous cell carcinoma from oral lichen planus by salivary metabolomics. Oral Diseases, 26(1), 35-42. https://doi.org/10.1111/odi.13209
Kordbacheh, F., Bhatia, N., & Farah, C. (2016). Patterns of differentially expressed genes in oral mucosal lesions visualised under autofluorescence (VELscope™). Oral Diseases, 22(4), 285-296. https://doi.org/10.1111/odi.12438
Lapa, R. M. L., Barros-Filho, M. C., Marchi, F. A., Domingues, M. A. C., de Carvalho, G. B., Drigo, S. A., … Rogatto, S. R. (2019). Integrated miRNA and mRNA expression analysis uncovers drug targets in laryngeal squamous cell carcinoma patients. Oral Oncology, 93, 76-84. https://doi.org/10.1016/j.oraloncology.2019.04.018
McCullough, M., Prasad, G., & Farah, C. S. (2010). Oral mucosal malignancy and potentially malignant lesions: An update on the epidemiology, risk factors, diagnosis and management. Australian Dental Journal, 55, 61-65. https://doi.org/10.1111/j.1834-7819.2010.01200.x
Mehrotra, R., Singh, M., Thomas, S., Nair, P., Pandya, S., Nigam, N. S., & Shukla, P. (2010). A cross-sectional study evaluating chemiluminescence and autofluorescence in the detection of clinically innocuous precancerous and cancerous oral lesions. Journal of the American Dental Association, 141, 151-156. https://doi.org/10.14219/jada.archive.2010.0132
Meleti, M., Giovannacci, I., Vescovi, P., Pedrazzi, G., Govoni, P., & Magnoni, C. (2020). Histopathological determinants of autofluorescence patterns in oral carcinoma. Oral Diseases, https://doi.org/10.1111/odi.13304
Nagi, R., Reddy-Kantharaj, Y. B., Rakesh, N., Janardhan-Reddy, S., & Sahu, S. (2016). Efficacy of light based detection systems for early detection of oral cancer and oral potentially malignant disorders: Systematic review. Medicina Oral Patología Oral Y Cirugia Bucal, 21(4), e447-e455. https://doi.org/10.4317/medoral.21104
Pavlova, I., Williams, M., El-Naggar, A., Richards-Kortum, R., & Gillenwater, A. (2008). Understanding the biological basis of autofluorescence imaging for oral cancer detection: High-resolution fluorescence microscopy in viable tissue. Clinical Cancer Research, 14(8), 2396-2404. https://doi.org/10.1158/1078-0432.CCR-07-1609
Poh, C. F., MacAulay, C. E., Zhang, L., & Rosin, M. P. (2009). Tracing the "at-risk" oral mucosa field with autofluorescence: Steps toward clinical impact. Cancer Prevention Research, 2(5), 401-404. https://doi.org/10.1158/1940-6207.CAPR-09-0060
Poh, C. F., Zhang, L. W., Anderson, D. W., Durham, J. S., Williams, P. M., Priddy, R. W., … Rosin, M. P. (2006). Fluorescence visualization detection of field alterations in tumor margins of oral cancer patients. Clinical Cancer Research, 12, 6716-6722. https://doi.org/10.1158/1078-0432.CCR-06-1317
Robledo-Sierra, J., Ben-Amy, D. P., Varoni, E., Bavarian, R., Simonsen, J. L., Paster, B. J., … Frandsen Lau, E. (2019). World Workshop on Oral Medicine VII: Targeting the oral microbiome Part 2: Current knowledge on malignant and potentially malignant oral disorders. Oral Diseases, 25(Suppl 1), 28-48. https://doi.org/10.1111/odi.13107
Routray, S., Kheur, S. M., & Kheur, M. (2013). Osteopontin: A marker for invasive oral squamous cell carcinoma but not for potentially malignant epithelial dysplasias. Annals of Diagnostic Pathology, 17(5), 421-424. https://doi.org/10.1016/j.anndiagpath.2013.03.005
Shu, Z., Li, P., Yu, B., Huang, S., & Chen, Y. (2020). The effectiveness of probiotics in prevention and treatment of cancer therapy-induced oral mucositis: A systematic review and meta-analysis. Oral Oncology, 102, 104559. https://doi.org/10.1016/j.oraloncology.2019
Slaughter, D. P., Southwick, H. W., & Smejkal, W. (1953). Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer, 6, 963. https://doi.org/10.1002/1097-0142(195309)6:5<963:aid-cncr2820060515>3.0.co;2-q
Sun, J.-M., Jun, H. J., Ko, Y. H., Park, Y. H., Ahn, Y. C., Son, Y.-I., … Ahn, M.-J. (2011). Insulin-like growth factor binding protein-3, in association with IGF-1 receptor, can predict prognosis in squamous cell carcinoma of the head and neck. Oral Oncology, 47(8), 714-719. https://doi.org/10.1016/j.oraloncology.2011.06.007
Tiwari, L., Kujan, O., & Farah, C. S. (2020a). Optical fluorescence imaging in oral cancer and potentially malignant disorders: A systematic review. Oral Diseases, 26(3), 491-510. https://doi.org/10.1111/odi.13071
Tiwari, L., Kujan, O., & Farah, C. S. (2020b). Clinico-pathological correlation of optical fluorescence imaging in oral mucosal lesions. Oral Diseases, https://doi.org/10.1111/odi.13334
Villa, A., Celentano, A., Glurich, I., Borgnakke, W. S., Jensen, S. B., Peterson, D. E., … Farah, C. S. (2019). World Workshop on Oral Medicine VII: Prognostic biomarkers in oral leukoplakia: A systematic review of longitudinal studies. Oral Disease, 25(Suppl. 1), 64-78. https://doi.org/10.1111/odi.13087
Villa, A., Hanna, G. J., Kacew, A., Frustino, J., Hammerman, P. S., & Woo, S. B. (2019). Oral keratosis of unknown significance shares genomic overlap with oral dysplasia. Oral Diseases, 25(7), 1707-1714. https://doi.org/10.1111/odi.13155
Vonk, J., de Wit, J. G., Voskuil, F. J., & Witjes, M. J. H. (2020). Improving oral cavity cancer diagnosis and treatment with fluorescence molecular imaging. Oral Diseases, https://doi.org/10.1111/odi.13308
Warnakulasuriya, S. (2009). Global epidemiology of oral and oropharyngeal cancer. Oral Oncology, 45(4-5), 309-316. https://doi.org/10.1016/j.oraloncology.2008.06.002
Warnakulasuriya, S. (2018). Clinical features and presentation of oral potentially malignant disorders. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 125(6), 582-590. https://doi.org/10.1016/j.oooo.2018.03.011
Warnakulasuriya, S., & Ariyawardana, A. (2016). Malignant transformation of oral leukoplakia: A systematic review of observational studies. Journal of Oral Pathology and Medicine, 2016(45), 155-166. https://doi.org/10.1111/jop.12339
Warnakulasuriya, S., Johnson, N. W., & Waal, I. V. D. (2017). Nomenclature and classification of potentially malignant disorders of the oral mucosa. Journal of Oral Pathology and Medicine, 36(10), 575-580. https://doi.org/10.1111/j.1600-0714.2007.00582.x
Warnakulasuriya, S., Reibel, J., Bouquot, J., & Dabelsteen, E. (2008). Oral epithelial dysplasia classification systems: Predictive value, utility, weaknesses and scope for improvement. Journal of Oral Pathology and Medicine, 37, 127-133. https://doi.org/10.1111/j.1600-0714.2007.00584.x
Yamamoto, N., Kawaguchi, K., Fujihara, H., Hasebe, M., Kishi, Y., Yasukawa, M., … Hamada, Y. (2017). Detection accuracy for epithelial dysplasia using an objective autofluorescence visualization method based on the luminance ratio. Int. Journal of Oral Science, 10;9(11), e2. https://doi.org/10.1038/ijos.2017.37
Yang, X., Shi, L., Zhou, Z., & Liu, W. (2019). Retrospective analysis of oral erythroplakia focused on multiple and multifocal malignant behavior. Oral Diseases, 25(7), 1829-1830. https://doi.org/10.1111/odi.13144
Yen, Y. C., Hsiao, J. R., Jiang, S. S., Chang, J. S., Wang, S. H., Shen, Y. Y., Chen, Y. W. (2015). Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1. Oncotarget, 6(39), 41837-41855. https://doi.org/10.18632/oncotarget.5995
Zolea, F., Biamonte, F., Battaglia, A. M., Faniello, M. C., Cuda, G., & Costanzo, F. (2016). Caffeine positively modulates ferritin heavy chain expression in H460 cells: Effects on cell proliferation. PLoS One, 11(9), e0163078. https://doi.org/10.1371/journal.pone.0163078