Continuous capture of recombinant antibodies by ZnCl
IgG
downstream processing
precipitation
purification
zinc
Journal
Engineering in life sciences
ISSN: 1618-0240
Titre abrégé: Eng Life Sci
Pays: Germany
ID NLM: 101193313
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
04
12
2019
revised:
18
02
2020
accepted:
05
03
2020
entrez:
11
7
2020
pubmed:
11
7
2020
medline:
11
7
2020
Statut:
epublish
Résumé
The capture of recombinant antibodies from cell culture broth is the first critical step of downstream processing. We were able to develop a precipitation-based method for the capture and purification of monoclonal antibodies based on divalent cations, namely ZnCl
Identifiants
pubmed: 32647505
doi: 10.1002/elsc.201900160
pii: ELSC1296
pmc: PMC7336134
doi:
Types de publication
Journal Article
Langues
eng
Pagination
265-274Informations de copyright
© 2020 The Authors. Engineering in Life Sciences published by Wiley‐VCH Verlag GmbH & Co. KGaA.
Déclaration de conflit d'intérêts
The authors have declared no conflict of interest.
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