Surgical management of thymic epithelial tumors.
Chemoradiotherapy, Adjuvant
Combined Modality Therapy
Cytoreduction Surgical Procedures
/ methods
Humans
Induction Chemotherapy
Minimally Invasive Surgical Procedures
/ methods
Neoplasm Invasiveness
Neoplasm Recurrence, Local
/ surgery
Neoplasms, Glandular and Epithelial
/ pathology
Reoperation
Sternotomy
Thoracic Surgery, Video-Assisted
Thymectomy
/ methods
Thymoma
/ surgery
Thymus Neoplasms
/ pathology
Treatment Outcome
Adjuvant therapy
Approach
Surgery
Thymic malignancy
Journal
Surgery today
ISSN: 1436-2813
Titre abrégé: Surg Today
Pays: Japan
ID NLM: 9204360
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
19
05
2020
accepted:
05
06
2020
pubmed:
11
7
2020
medline:
16
6
2021
entrez:
11
7
2020
Statut:
ppublish
Résumé
Resection is the mainstay of treatment for thymic epithelial tumors (TETs), with complete removal of the tumor and involved organs being the ultimate aim. The choice of surgical approach plays a major role in defining treatment success, and the optimal choice of method should thus provide an adequate surgical view to achieve complete tumor resection. While median sternotomy is considered the gold standard for access to the mediastinum, several minimally invasive approaches to thymectomy have been described, including video-assisted robotic-assisted thymectomy, although the oncological outcomes of that procedure remain unclear. A multimodal approach incorporating chemotherapy or chemoradiotherapy followed by extended surgery may improve resectability and outcomes for patients with advanced TETs. Surgical debulking is also reportedly acceptable for invasive thymoma because of its potential for achieving favorable outcomes. Re-resection is an acceptable option for patients with recurrent thymoma after initial resection, and repeat resection for recurrent pleural dissemination seems effective. Here, the literature on current clinical practices in the surgical management and treatment of TETs is reviewed.
Identifiants
pubmed: 32647929
doi: 10.1007/s00595-020-02070-y
pii: 10.1007/s00595-020-02070-y
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
331-339Références
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