Need for Speed: From Human SARS-CoV-2 Samples to Protective and Efficacious Antibodies in Weeks.


Journal

Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066

Informations de publication

Date de publication:
09 07 2020
Historique:
entrez: 11 7 2020
pubmed: 11 7 2020
medline: 18 7 2020
Statut: ppublish

Résumé

The emergence of SARS-CoV-2 has driven a global research effort to identify medical countermeasures at an unprecedented pace. In this issue of Cell, Cao et al. identify thousands of SARS-CoV-2 neutralizing antibodies from convalescent donors. The authors improve our understanding of immunity against the coronavirus spike glycoprotein and detail novel pathways to rapidly identify and characterize protective monoclonal antibodies.

Identifiants

pubmed: 32649880
pii: S0092-8674(20)30748-0
doi: 10.1016/j.cell.2020.06.017
pmc: PMC7346785
pii:
doi:

Substances chimiques

Antibodies, Viral 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

7-9

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Références

Science. 2020 Mar 13;367(6483):1260-1263
pubmed: 32075877
Cell. 2020 Jul 9;182(1):73-84.e16
pubmed: 32425270
Science. 2020 Aug 7;369(6504):650-655
pubmed: 32571838
Cell. 2020 Apr 16;181(2):281-292.e6
pubmed: 32155444
Immunol Rev. 2016 Mar;270(1):65-77
pubmed: 26864105
Cell. 2016 Jul 28;166(3):609-623
pubmed: 27453470
Am J Pathol. 2020 Aug;190(8):1680-1690
pubmed: 32473109
Nature. 2020 Aug;584(7819):120-124
pubmed: 32454512
J Virol. 2018 Apr 27;92(10):
pubmed: 29514901

Auteurs

M Gordon Joyce (MG)

Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. Electronic address: gjoyce@eidresearch.org.

Adam K Wheatley (AK)

Department of Microbiology and Immunology, University of Melbourne, at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.

Kayvon Modjarrad (K)

Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.

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Classifications MeSH