Stress and cancer. Part I: Mechanisms mediating the effect of stressors on cancer.
Cancer
Cortisol
Epinephrine
Hypothalamic-pituitary-adrenocortical axis
Neurobiology of cancer
Norepinephrine
Stress
Sympathoadrenal system
β-Blockers
Journal
Journal of neuroimmunology
ISSN: 1872-8421
Titre abrégé: J Neuroimmunol
Pays: Netherlands
ID NLM: 8109498
Informations de publication
Date de publication:
03 Jul 2020
03 Jul 2020
Historique:
received:
02
01
2020
revised:
25
06
2020
accepted:
26
06
2020
pubmed:
12
7
2020
medline:
12
7
2020
entrez:
12
7
2020
Statut:
aheadofprint
Résumé
Observations indicating a link between psychosocial stress and cancer can be traced back almost 2 millennia. However, the pathways and mechanisms interconnecting them has only been elucidated in more detail since the end of the 20th century. Importantly, recently accumulated evidences have confirmed the ability of stress to promote the induction and progression of cancer. The main aim of this review is to describe the pathways and mechanisms mediating the stimulatory effects of the neuroendocrine stress response on the induction of cancer, potentiation of cancer growth, and the development of metastases.
Identifiants
pubmed: 32652365
pii: S0165-5728(20)30003-5
doi: 10.1016/j.jneuroim.2020.577311
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
577311Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest We declare no conflicts of interest.