Botulinum toxin therapy improves masseter spasticity in Amyotrophic Lateral Sclerosis.
Amyotrophic Lateral Sclerosis
Botulinum toxin
Masseter
Spasticity
Trismus
Journal
Revue neurologique
ISSN: 0035-3787
Titre abrégé: Rev Neurol (Paris)
Pays: France
ID NLM: 2984779R
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
01
02
2020
revised:
18
04
2020
accepted:
20
04
2020
pubmed:
13
7
2020
medline:
5
8
2021
entrez:
13
7
2020
Statut:
ppublish
Résumé
Fifteen ALS patients, with troublesome symptoms linked to masseter spasticity, benefited from BoNT-A injections in each masseter. Based on the medical records of patients, the effect of the first injection was assessed one month later. We retrospectively collected information for 12 patients. Eight of them reported a beneficial effect after the injection for the following symptoms: trismus, tongue, lip and cheek biting, and jaw clonus. Five patients indicated that dental care was easier after injection. Our study showed that injections of BoNT-A unequivocally reduced masseter spasticity in ALS patients who subsequently enjoyed greater comfort in their daily living.
Identifiants
pubmed: 32653215
pii: S0035-3787(20)30603-2
doi: 10.1016/j.neurol.2020.04.022
pii:
doi:
Substances chimiques
Botulinum Toxins, Type A
EC 3.4.24.69
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
870-873Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.