Evaluation of platelet-rich plasma as a treatment for androgenetic alopecia: A randomized controlled trial.
androgenetic alopecia
female pattern hair loss
hair
male pattern hair loss
platelet-rich plasma
randomized controlled trial
Journal
Journal of the American Academy of Dermatology
ISSN: 1097-6787
Titre abrégé: J Am Acad Dermatol
Pays: United States
ID NLM: 7907132
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
15
05
2020
revised:
02
07
2020
accepted:
04
07
2020
pubmed:
13
7
2020
medline:
10
4
2021
entrez:
13
7
2020
Statut:
ppublish
Résumé
Platelet-rich plasma (PRP) shows promise as an androgenetic alopecia (AGA) treatment. To conduct a randomized placebo-controlled split-scalp study to investigate the effects of PRP on hair regrowth and thickness. Two 7.6-cm × 7.6-cm squares were tattooed on the scalps of 35 study participants with AGA. Areas were randomly assigned to intradermal injection with PRP or saline. Participants received 3 monthly treatment sessions with evaluation 3 months after the final treatment. Hair density in the PRP-treated area was significantly increased compared with baseline at all visits. At the final assessment, hair density in PRP-treated areas increased from 151 ± 39.82 hairs/cm Possible PRP diffusion due to split-scalp study design as well as microinjections causing microinjury to both sides. PRP may have benefit in increasing hair density.
Sections du résumé
BACKGROUND
BACKGROUND
Platelet-rich plasma (PRP) shows promise as an androgenetic alopecia (AGA) treatment.
OBJECTIVE
OBJECTIVE
To conduct a randomized placebo-controlled split-scalp study to investigate the effects of PRP on hair regrowth and thickness.
METHODS
METHODS
Two 7.6-cm × 7.6-cm squares were tattooed on the scalps of 35 study participants with AGA. Areas were randomly assigned to intradermal injection with PRP or saline. Participants received 3 monthly treatment sessions with evaluation 3 months after the final treatment.
RESULTS
RESULTS
Hair density in the PRP-treated area was significantly increased compared with baseline at all visits. At the final assessment, hair density in PRP-treated areas increased from 151 ± 39.82 hairs/cm
LIMITATIONS
CONCLUSIONS
Possible PRP diffusion due to split-scalp study design as well as microinjections causing microinjury to both sides.
CONCLUSION
CONCLUSIONS
PRP may have benefit in increasing hair density.
Identifiants
pubmed: 32653577
pii: S0190-9622(20)32170-8
doi: 10.1016/j.jaad.2020.07.006
pii:
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
1298-1303Commentaires et corrections
Type : CommentIn
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2020 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.