Discordant courses of COVID-19 in a cohabiting couple of lung transplant recipients.
COVID-19
SARS-CoV-2
cystic fibrosis
immunosuppression
lung transplant
viral pneumonia
Journal
Transplant infectious disease : an official journal of the Transplantation Society
ISSN: 1399-3062
Titre abrégé: Transpl Infect Dis
Pays: Denmark
ID NLM: 100883688
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
01
07
2020
accepted:
05
07
2020
pubmed:
13
7
2020
medline:
5
3
2021
entrez:
13
7
2020
Statut:
ppublish
Résumé
COVID-19 is a novel infectious disease caused by SARS-CoV-2 that emerged in late 2019 and which is now a pandemic. Solid organ transplant recipients are perceived to be at increased risk of severe COVID-19 due to their chronic use of immunosuppressive drugs (ISDs) and to their associated conditions. Scarce data are available on the optimized management of ISDs in these patients and on its impact on presentation, clinical course, viral shedding, and outcome. We report here two cases of COVID-19 in a cohabiting couple of lung transplant recipients for cystic fibrosis, who had different ISDs management and who developed discordant courses of their disease. Our findings suggest that the degree of their immunosuppression might be a reason for their different course and that ISDs might prove partially protective.
Identifiants
pubmed: 32654244
doi: 10.1111/tid.13410
pmc: PMC7404422
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13410Informations de copyright
© 2020 Wiley Periodicals LLC.
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