Aberrant DNA methylation levels of the

DNA methylation Obstructive sleep apnea formyl peptide receptor intermittent hypoxia with re-oxygenation

Journal

American journal of translational research
ISSN: 1943-8141
Titre abrégé: Am J Transl Res
Pays: United States
ID NLM: 101493030

Informations de publication

Date de publication:
2020
Historique:
received: 10 08 2019
accepted: 15 04 2020
entrez: 14 7 2020
pubmed: 14 7 2020
medline: 14 7 2020
Statut: epublish

Résumé

FPR1 over-expression and insufficiency of FPR2 and FPR3 are associated with disease severity of obstructive sleep apnea (OSA). We hypothesized that epigenetic modification of the DNA methylation levels over 17 CpG sites of the Both -524 and -264 CpG sites of the Aberrant DNA methylation patterns of the

Sections du résumé

BACKGROUND BACKGROUND
FPR1 over-expression and insufficiency of FPR2 and FPR3 are associated with disease severity of obstructive sleep apnea (OSA). We hypothesized that epigenetic modification of the
METHODS METHODS
DNA methylation levels over 17 CpG sites of the
RESULTS RESULTS
Both -524 and -264 CpG sites of the
CONCLUSIONS CONCLUSIONS
Aberrant DNA methylation patterns of the

Identifiants

pubmed: 32655788
pmc: PMC7344102

Types de publication

Journal Article

Langues

eng

Pagination

2521-2537

Informations de copyright

AJTR Copyright © 2020.

Déclaration de conflit d'intérêts

None.

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Auteurs

Yung-Che Chen (YC)

Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.
Sleep Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.

Kuo-Tung Huang (KT)

Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.
Sleep Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.

Mao-Chang Su (MC)

Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.
Sleep Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.
Chang Gung University of Science and Technology Chia-yi, Taiwan.

Po-Yuan Hsu (PY)

Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.

Chien-Hung Chin (CH)

Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.
Sleep Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.
Chung Shan Medical University School of Medicine Taichung, Taiwan.

I-Chun Lin (IC)

Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.

Chia-Wei Liou (CW)

Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.

Ting-Ya Wang (TY)

Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.

Yong-Yong Lin (YY)

Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.

Chang-Chun Hsiao (CC)

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University Taoyuan 33302, Taiwan.

Meng-Chih Lin (MC)

Division of Pulmonary and Critical Care Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.
Sleep Center, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung 83301, Taiwan.

Classifications MeSH