Renal cell tumors convert natural killer cells to a proangiogenic phenotype.

angiogenesis immunosuppression innate immunity kidney cancer natural killer cells

Journal

Oncotarget
ISSN: 1949-2553
Titre abrégé: Oncotarget
Pays: United States
ID NLM: 101532965

Informations de publication

Date de publication:
30 Jun 2020
Historique:
received: 27 03 2020
accepted: 05 06 2020
entrez: 14 7 2020
pubmed: 14 7 2020
medline: 14 7 2020
Statut: epublish

Résumé

Natural killer (NK) cells are classically associated with immune surveillance and destruction of tumor cells. Inconsistent with this function, NK cells are found in advanced human tumors including renal cell carcinoma (RCC). NK cells with non-classical phenotypes (CD56

Identifiants

pubmed: 32655841
doi: 10.18632/oncotarget.27654
pii: 27654
pmc: PMC7335666
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2571-2585

Subventions

Organisme : NCI NIH HHS
ID : R01 CA199649
Pays : United States

Déclaration de conflit d'intérêts

CONFLICTS OF INTEREST The authors declare no conflicts of interest.

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Auteurs

Yue Guan (Y)

Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.

Christopher B Chambers (CB)

Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.

Taylor Tabatabai (T)

Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.

Ha Hatley (H)

Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.

Kristin R Delfino (KR)

Center for Clinical Research, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.

Kathy Robinson (K)

Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Simmons Cancer Institute, Springfield, IL 62702, USA.

Shaheen R Alanee (SR)

Department of Surgery, Division of Urology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Simmons Cancer Institute, Springfield, IL 62702, USA.

Sophia Ran (S)

Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Simmons Cancer Institute, Springfield, IL 62702, USA.

Donald S Torry (DS)

Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Simmons Cancer Institute, Springfield, IL 62702, USA.

Andrew Wilber (A)

Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Simmons Cancer Institute, Springfield, IL 62702, USA.

Classifications MeSH