SARS-CoV-2, COVID-19, skin and immunology - What do we know so far?
allergy
drug hypersensitivity
skin
virus
Journal
Allergy
ISSN: 1398-9995
Titre abrégé: Allergy
Pays: Denmark
ID NLM: 7804028
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
09
06
2020
revised:
29
06
2020
accepted:
06
07
2020
pubmed:
14
7
2020
medline:
19
3
2021
entrez:
14
7
2020
Statut:
ppublish
Résumé
The pandemic condition coronavirus disease (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can take asymptomatic, mild, moderate, and severe courses. COVID-19 affects primarily the respiratory airways leading to dry cough, fever, myalgia, headache, fatigue, and diarrhea and can end up in interstitial pneumonia and severe respiratory failure. Reports about the manifestation of various skin lesions and lesions of the vascular system in some subgroups of SARS-CoV-2-positive patients as such features outside the respiratory sphere, are rapidly emerging. Vesicular, urticarial, and maculopapular eruptions and livedo, necrosis, and other vasculitis forms have been reported most frequently in association with SARS-CoV-2 infection. In order to update information gained, we provide a systematic overview of the skin lesions described in COVID-19 patients, discuss potential causative factors, and describe differential diagnostic evaluations. Moreover, we summarize current knowledge about immunologic, clinical, and histologic features of virus- and drug-induced lesions of the skin and changes to the vascular system in order to transfer this knowledge to potential mechanisms induced by SARS-CoV-2.
Identifiants
pubmed: 32658359
doi: 10.1111/all.14498
pmc: PMC7404682
doi:
Substances chimiques
ACE2 protein, human
EC 3.4.17.23
Angiotensin-Converting Enzyme 2
EC 3.4.17.23
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
698-713Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : EXC2151
Organisme : Deutsche Forschungsgemeinschaft
ID : 390873048
Informations de copyright
© 2020 The Authors. Allergy published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.
Références
J Eur Acad Dermatol Venereol. 2020 Jul;34(7):e306-e307
pubmed: 32330340
JAAD Case Rep. 2020 Apr 18;6(6):489-492
pubmed: 32363225
Future Microbiol. 2017 Feb;12:171-193
pubmed: 27838923
Eur Heart J. 2020 May 14;41(19):1810-1817
pubmed: 32388565
Nat Rev Immunol. 2020 May;20(5):271-272
pubmed: 32296135
Science. 2005 Sep 16;309(5742):1864-8
pubmed: 16166518
JAMA. 1998 Apr 15;279(15):1200-5
pubmed: 9555760
N Engl J Med. 2020 Apr 16;382(16):1564-1567
pubmed: 32182409
J Med Virol. 2020 Sep;92(9):1580-1586
pubmed: 32249956
J Eur Acad Dermatol Venereol. 2020 Aug;34(8):e365-e368
pubmed: 32386459
Science. 2020 Mar 13;367(6483):1260-1263
pubmed: 32075877
Ann Pharmacother. 2002 Jan;36(1):130-47
pubmed: 11816242
J Eur Acad Dermatol Venereol. 2020 Sep;34(9):e457-e459
pubmed: 32386448
Br J Dermatol. 2020 Jul;183(1):71-77
pubmed: 32348545
N Engl J Med. 2020 Oct 15;383(16):1522-1534
pubmed: 32558485
Pediatr Dermatol. 2020 May;37(3):435-436
pubmed: 32315079
Am J Respir Crit Care Med. 2020 Jul 1;202(1):83-90
pubmed: 32348692
PLoS One. 2015 May 26;10(5):e0127515
pubmed: 26010093
Am J Clin Dermatol. 2001;2(3):151-8
pubmed: 11705092
J Eur Acad Dermatol Venereol. 2020 May;34(5):e212-e213
pubmed: 32215952
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
J Am Acad Dermatol. 2020 Jul;83(1):280-285
pubmed: 32305439
Obesity (Silver Spring). 2020 Oct;28(10):1806-1810
pubmed: 32589784
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
Allergy. 2021 Mar;76(3):698-713
pubmed: 32658359
Dermatol Ther. 2020 Sep;33(5):e13549
pubmed: 32390279
Cell Discov. 2020 Feb 24;6:11
pubmed: 32133153
Lancet. 2020 May 2;395(10234):1417-1418
pubmed: 32325026
N Engl J Med. 2020 Apr 30;382(18):1708-1720
pubmed: 32109013
Am J Clin Dermatol. 2019 Apr;20(2):217-236
pubmed: 30652265
J Eur Acad Dermatol Venereol. 2020 Oct;34(10):e579-e581
pubmed: 32531119
Curr Opin Infect Dis. 2015 Apr;28(2):139-50
pubmed: 25706914
J Am Acad Dermatol. 2020 May;82(5):e177
pubmed: 32213305
JAMA Dermatol. 2020 Sep 1;156(9):998-1003
pubmed: 32584377
Nat Med. 2020 Apr;26(4):450-452
pubmed: 32284615
J Allergy Clin Immunol. 2020 Jul;146(1):110-118
pubmed: 32294485
Clin Exp Dermatol. 2020 Oct;45(7):892-895
pubmed: 32385858
Am J Dermatopathol. 2015 Feb;37(2):93-106
pubmed: 25171430
Pediatr Dermatol. 2020 May;37(3):442-446
pubmed: 32445583
Med Hypotheses. 2020 Nov;144:110015
pubmed: 32592919
J Allergy Clin Immunol. 2012 Nov;130(5):1225-1225.e6
pubmed: 23116633
Cell. 2020 May 28;181(5):1016-1035.e19
pubmed: 32413319
EMBO J. 2005 Apr 20;24(8):1634-43
pubmed: 15791205
Nat Rev Immunol. 2008 Jul;8(7):512-22
pubmed: 18469829
Allergy. 2020 Jul;75(7):1822-1824
pubmed: 32401346
Immunity. 2020 Jun 16;52(6):910-941
pubmed: 32505227
JAMA Dermatol. 2020 Sep 1;156(9):992-997
pubmed: 32584397
Environ Int. 2020 Jun;139:105730
pubmed: 32294574
Br J Dermatol. 2020 Oct;183(4):778-780
pubmed: 32585767
Obesity (Silver Spring). 2020 Jul;28(7):1187-1190
pubmed: 32339391
Rheumatology (Oxford). 2009 May;48(5):475-82
pubmed: 19258377
J Eur Acad Dermatol Venereol. 2020 Nov;34(11):e686-e689
pubmed: 32589293
Allergy. 2020 Oct;75(10):2503-2541
pubmed: 32535955
Clin Dermatol. 1999 Sep-Oct;17(5):509-14
pubmed: 10590844
Cell. 2020 May 14;181(4):954-954.e1
pubmed: 32413300
Allergy. 2020 Jul;75(7):1699-1709
pubmed: 32196678
N Engl J Med. 2020 Aug 20;383(8):789-790
pubmed: 32530585
Nat Rev Immunol. 2016 Oct;16(10):626-38
pubmed: 27546235
Allergy. 2020 Nov;75(11):2829-2845
pubmed: 32496587
Nat Rev Immunol. 2010 Jul;10(7):514-26
pubmed: 20577268
JAMA. 1986 Dec 26;256(24):3358-63
pubmed: 2946876
Am J Dermatopathol. 2015 Jan;37(1):1-14; quiz 12-4
pubmed: 25171431
Am J Clin Dermatol. 2009;10(1):9-21
pubmed: 19170406
J Am Acad Dermatol. 2020 Sep;83(3):e241
pubmed: 32497704
Trends Immunol. 2009 Jul;30(7):301-5
pubmed: 19541537
J Eur Acad Dermatol Venereol. 2020 Nov;34(11):2499-2504
pubmed: 32585074
J Eur Acad Dermatol Venereol. 2020 Oct;34(10):e561-e563
pubmed: 32495400
Allergy. 2020 Jul;75(7):1564-1581
pubmed: 32396996
Nat Med. 2020 Jul;26(7):1070-1076
pubmed: 32514174
Lancet. 2020 Jun 6;395(10239):1771-1778
pubmed: 32410760
Int J Oral Sci. 2020 Apr 17;12(1):11
pubmed: 32300101
J Cutan Pathol. 2017 Dec;44(12):1038-1048
pubmed: 28914958
Allergy. 2020 Jul;75(7):1809-1812
pubmed: 32281110
J Med Virol. 2020 Jun;92(6):577-583
pubmed: 32162702
Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):11875-11877
pubmed: 32404416
Pediatr Dermatol. 2020 May;37(3):406-411
pubmed: 32386460
Transl Res. 2020 Jun;220:1-13
pubmed: 32299776
Ann Intern Med. 2020 May 05;172(9):577-582
pubmed: 32150748
Infect Dis Poverty. 2020 Apr 28;9(1):45
pubmed: 32345362
Nat Rev Immunol. 2008 Sep;8(9):737-44
pubmed: 18728636
Am J Med. 2008 Apr;121(4):258-64
pubmed: 18374680
Int J Dermatol. 2020 Jun;59(6):739-743
pubmed: 32329897
Int J Mol Sci. 2020 Apr 22;21(8):
pubmed: 32331343
Cell. 2020 Apr 16;181(2):271-280.e8
pubmed: 32142651
Eur J Histochem. 2008 Jan-Mar;52(1):39-44
pubmed: 18502721
Asian Pac J Allergy Immunol. 2020 Mar;38(1):1-9
pubmed: 32105090
Nat Rev Immunol. 2020 Jun;20(6):363-374
pubmed: 32346093
Mol Metab. 2020 Sep;39:101044
pubmed: 32585364
Nat Med. 2020 May;26(5):681-687
pubmed: 32327758
Curr Rheumatol Rep. 2008 Dec;10(6):449-52
pubmed: 19007534
Cardiovasc Res. 2020 Aug 1;116(10):1666-1687
pubmed: 32352535
J Eur Acad Dermatol Venereol. 2020 Aug;34(8):e373-e375
pubmed: 32386446
Front Med. 2020 Apr;14(2):117-125
pubmed: 32318975
J Pathol. 2020 Jul;251(3):228-248
pubmed: 32418199
Curr Opin Allergy Clin Immunol. 2019 Aug;19(4):294-301
pubmed: 31135394
Lancet Infect Dis. 2020 May;20(5):515-516
pubmed: 32213336