Defense mechanisms to increasing back pressure for hepatic oxygen transport and venous return in porcine fecal peritonitis.


Journal

American journal of physiology. Gastrointestinal and liver physiology
ISSN: 1522-1547
Titre abrégé: Am J Physiol Gastrointest Liver Physiol
Pays: United States
ID NLM: 100901227

Informations de publication

Date de publication:
01 09 2020
Historique:
pubmed: 14 7 2020
medline: 15 12 2020
entrez: 14 7 2020
Statut: ppublish

Résumé

High central venous pressure (CVP) acutely decreases venous return. How this affects hepatic oxygen transport in sepsis remains unclear. The aim of this study was to evaluate the effects of repeated increases in CVP via standard nursing procedures (NPs) on hepato-splanchnic and renal oxygen transport in a prolonged porcine sepsis model. Twenty anesthetized and mechanically ventilated pigs with regional hemodynamics monitored were randomized to fecal peritonitis or controls (

Identifiants

pubmed: 32658622
doi: 10.1152/ajpgi.00216.2020
doi:

Substances chimiques

Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

G289-G302

Auteurs

Shengchen Liu (S)

Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.

Pedro Paulo Zanella do Amaral Campos (PPZ)

Department of Intensive Care Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

Daniela Casoni (D)

Experimental Surgery Facility, Department for BioMedical Research, University of Bern, Bern, Switzerland.

David Berger (D)

Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Andreas Kohler (A)

Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Andreas Bloch (A)

Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

David Bervini (D)

Department of Neurosurgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Florian Setzer (F)

Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

David R Cameron (DR)

Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Werner Z'Graggen (W)

Department of Neurosurgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Anisa Hana (A)

Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Rupert Langer (R)

Institue of Pathology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Thiago D Corrêa (TD)

Department of Intensive Care Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

Guido Beldi (G)

Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Jukka Takala (J)

Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Stephan M Jakob (SM)

Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

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Classifications MeSH