Obturator nerve injury in a chemo and radio-resistant patient with a locally-advanced cervical cancer after two previous uterine artery embolizations for severe vaginal bleeding: Case report and review of literature.


Journal

European journal of obstetrics, gynecology, and reproductive biology
ISSN: 1872-7654
Titre abrégé: Eur J Obstet Gynecol Reprod Biol
Pays: Ireland
ID NLM: 0375672

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 05 01 2020
revised: 21 06 2020
accepted: 01 07 2020
pubmed: 14 7 2020
medline: 15 5 2021
entrez: 14 7 2020
Statut: ppublish

Résumé

Chemo and radiotherapy are actually the gold standard of treatment for locally-advanced cervical cancer. We report a case report showing a repaired (video 1) right obturator nerve after an incidental injury during a right internal iliac artery closure with 10 mm titanium clip for severe pelvic bleeding in a patient with locally-advanced cervical cancer. A 52 year-old postmenopausal woman with a chemo and radio-resistant locally-advanced squamous cervical cancer was admitted at our department for severe vaginal bleeding after two previous uterine artery embolizations. As a consequence of the increasing vaginal bleeding, and after a MRI-scan, an open surgical treatment was decided with a type C radical hysterectomy with bilateral salpingo-oophorectomy. During dissection of obturator, paravescical and pararectal spaces and removal of metastatic pelvic lymphnodes, a severe blood loss that required a right internal iliac artery closure with 10 mm titanium clip was observed. A right obturator nerve incidental injury during this time occurred. After an immediate grasping of the two sides of the lesion, the obturator nerve was succesfully repaired using 4-0 Prolene interrupted sutures (Ethicon, Johnson & Johnson, New Jersey, USA). The patient was regularly discharged four days after the surgical procedure without neurological deficit, paresthesia or side effects. In conclusion obturator nerve repair is an emergency procedure for treatment of patients with advanced cervical cancer, but it should be reserved for oncologic surgeons trained in extensive oncological procedures and repair of nerve and vascular injuries potentially associated with high mortality rate.

Identifiants

pubmed: 32659642
pii: S0301-2115(20)30442-5
doi: 10.1016/j.ejogrb.2020.07.002
pii:
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

355-358

Informations de copyright

Copyright © 2020. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that there are no conflicts of interest.

Auteurs

Raffaele Tinelli (R)

Department of Obstetrics and Gynecology, "Valle d'Itria" Hospital, Martina Franca, via San Francesco da Paola, 74015 Taranto, Italy. Electronic address: raffaeletinelli@gmail.com.

Stefano Uccella (S)

Departments of Obstetrics and Gynecology, Ospedale degli Infermi, Biella, Italy.

Luigi Nappi (L)

Department of Obstetrics and Gynecology, University of Foggia, Italy.

Giuseppe D'Amato (G)

Head of IVF Unit, "Jaja" Hospital, Conversano, Bari, Italy.

Ettore Cicinelli (E)

Department of Obstetrics and Gynecology, University of Bari, Italy.

Stefano Angioni (S)

Department of Obstetrics and Gynecology, Presidio Policlinico di Monserrato, University of Cagliari, Monserrato, Italy.

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