Effect of Vitamin D Supplementation on Inflammatory Markers in Non-Obese Lebanese Patients with Type 2 Diabetes: A Randomized Controlled Trial.
Aged
Blood Glucose
/ analysis
C-Reactive Protein
/ analysis
Cholecalciferol
/ administration & dosage
Diabetes Mellitus, Type 2
/ blood
Dietary Supplements
Female
Humans
Insulin Resistance
Interleukin-6
/ blood
Lebanon
Male
Tumor Necrosis Factor-alpha
/ blood
Vitamin D
/ analogs & derivatives
Vitamin D Deficiency
/ blood
Vitamins
/ administration & dosage
IL-6
TNF-α
hs-CRP
type 2 diabetes mellitus
vitamin D
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
09 Jul 2020
09 Jul 2020
Historique:
received:
03
06
2020
revised:
03
07
2020
accepted:
07
07
2020
entrez:
15
7
2020
pubmed:
15
7
2020
medline:
3
3
2021
Statut:
epublish
Résumé
A low serum 25-hydroxyvitamin D (25(OH) D) concentration has been associated with a higher risk of type 2 diabetes mellitus (T2DM), especially in older people. Our aim in this randomized controlled trial was to evaluate the effect of vitamin D treatment on inflammatory markers in non-obese Lebanese patients with T2DM, living in Beirut, Lebanon. Non-Obese patients with T2DM ( The vitamin D group showed higher blood levels of (25(OH) D) ( Six months of vitamin D supplementation led to a decrease in some inflammatory markers in patients with T2DM. Additional studies with a larger sample and a longer period are advised in this regard. This trial was registered at ClinicalTrial.gov; Identifier number: NCT03782805.
Sections du résumé
BACKGROUND
BACKGROUND
A low serum 25-hydroxyvitamin D (25(OH) D) concentration has been associated with a higher risk of type 2 diabetes mellitus (T2DM), especially in older people. Our aim in this randomized controlled trial was to evaluate the effect of vitamin D treatment on inflammatory markers in non-obese Lebanese patients with T2DM, living in Beirut, Lebanon.
METHODS
METHODS
Non-Obese patients with T2DM (
RESULTS
RESULTS
The vitamin D group showed higher blood levels of (25(OH) D) (
CONCLUSION
CONCLUSIONS
Six months of vitamin D supplementation led to a decrease in some inflammatory markers in patients with T2DM. Additional studies with a larger sample and a longer period are advised in this regard. This trial was registered at ClinicalTrial.gov; Identifier number: NCT03782805.
Identifiants
pubmed: 32659891
pii: nu12072033
doi: 10.3390/nu12072033
pmc: PMC7400886
pii:
doi:
Substances chimiques
Blood Glucose
0
IL6 protein, human
0
Interleukin-6
0
Tumor Necrosis Factor-alpha
0
Vitamins
0
Vitamin D
1406-16-2
Cholecalciferol
1C6V77QF41
C-Reactive Protein
9007-41-4
25-hydroxyvitamin D
A288AR3C9H
Banques de données
ClinicalTrials.gov
['NCT03782805']
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
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