Pencil-paper on-skin electronics.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
04 08 2020
Historique:
pubmed: 15 7 2020
medline: 23 9 2020
entrez: 15 7 2020
Statut: ppublish

Résumé

Pencils and papers are ubiquitous in our society and have been widely used for writing and drawing, because they are easy to use, low-cost, widely accessible, and disposable. However, their applications in emerging skin-interfaced health monitoring and interventions are still not well explored. Herein, we report a variety of pencil-paper-based on-skin electronic devices, including biophysical (temperature, biopotential) sensors, sweat biochemical (pH, uric acid, glucose) sensors, thermal stimulators, and humidity energy harvesters. Among these devices, pencil-drawn graphite patterns (or combined with other compounds) serve as conductive traces and sensing electrodes, and office-copy papers work as flexible supporting substrates. The enabled devices can perform real-time, continuous, and high-fidelity monitoring of a range of vital biophysical and biochemical signals from human bodies, including skin temperatures, electrocardiograms, electromyograms, alpha, beta, and theta rhythms, instantaneous heart rates, respiratory rates, and sweat pH, uric acid, and glucose, as well as deliver programmed thermal stimulations. Notably, the qualities of recorded signals are comparable to those measured with conventional methods. Moreover, humidity energy harvesters are prepared by creating a gradient distribution of oxygen-containing groups on office-copy papers between pencil-drawn electrodes. One single-unit device (0.87 cm

Identifiants

pubmed: 32661158
pii: 2008422117
doi: 10.1073/pnas.2008422117
pmc: PMC7414167
doi:

Substances chimiques

Graphite 7782-42-5

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

18292-18301

Subventions

Organisme : NINDS NIH HHS
ID : R01 NS069726
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS094539
Pays : United States

Déclaration de conflit d'intérêts

The authors declare no competing interest.

Références

Acc Chem Res. 2019 Mar 19;52(3):523-533
pubmed: 30767497
Nat Biotechnol. 2019 Apr;37(4):389-406
pubmed: 30804534
Chem Soc Rev. 2019 Jun 4;48(11):2946-2966
pubmed: 31073551
Adv Mater. 2019 Jan;31(2):e1805705
pubmed: 30444018
Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):205-213
pubmed: 31871158
Sci Adv. 2019 Nov 08;5(11):eaax0649
pubmed: 31723600
Nat Commun. 2016 May 23;7:11650
pubmed: 27212140
Nat Biotechnol. 2019 Apr;37(4):382-388
pubmed: 30940942
Sci Adv. 2018 Feb 09;4(2):eaaq0508
pubmed: 29487912
Adv Mater. 2020 Apr;32(15):e1902417
pubmed: 31206819
Sci Adv. 2018 Sep 21;4(9):eaau0920
pubmed: 30255151
Expert Rev Neurother. 2015 Apr;15(4):425-44
pubmed: 25779862
Nat Mater. 2017 Aug;16(8):834-840
pubmed: 28504674
Acc Chem Res. 2018 May 15;51(5):988-998
pubmed: 29664613
Sensors (Basel). 2013 Aug 09;13(8):10273-86
pubmed: 23939584
Chem Rev. 2019 Apr 24;119(8):5461-5533
pubmed: 30689360
Nature. 2016 Dec 14;540(7633):379-385
pubmed: 27974769
Neurosci Biobehav Rev. 2014 Jul;44:58-75
pubmed: 23116991
Nat Mater. 2015 Aug;14(8):785-9
pubmed: 26099109
Science. 2019 Mar 1;363(6430):
pubmed: 30819934
Science. 2011 Aug 12;333(6044):838-43
pubmed: 21836009
Nat Nanotechnol. 2017 Sep;12(9):907-913
pubmed: 28737748
J Clin Neurophysiol. 2004 Sep-Oct;21(5):341-52
pubmed: 15592008
Adv Mater. 2020 Apr;32(15):e1902743
pubmed: 31408223
Nat Biotechnol. 2020 Feb;38(2):217-224
pubmed: 31768044
Adv Mater. 2020 Apr;32(17):e1908475
pubmed: 32173920
Adv Mater. 2015 Nov 4;27(41):6423-30
pubmed: 26398335
Adv Mater. 2018 Dec;30(50):e1804327
pubmed: 30306662
Nat Commun. 2019 Jun 18;10(1):2676
pubmed: 31213599
Adv Mater. 2011 May 3;23(17):1935-61
pubmed: 21433116

Auteurs

Yadong Xu (Y)

Department of Biomedical, Biological & Chemical Engineering, University of Missouri, Columbia, MO 65211.

Ganggang Zhao (G)

Department of Mechanical & Aerospace Engineering, University of Missouri, Columbia, MO 65211.

Liang Zhu (L)

Department of Electrical and Computer Engineering, University of Illinois at Chicago, Chicago, IL 60607.

Qihui Fei (Q)

Department of Biomedical, Biological & Chemical Engineering, University of Missouri, Columbia, MO 65211.

Zhe Zhang (Z)

Department of Biomedical, Biological & Chemical Engineering, University of Missouri, Columbia, MO 65211.

Zanyu Chen (Z)

Department of Mechanical & Aerospace Engineering, University of Missouri, Columbia, MO 65211.

Fufei An (F)

Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801.

Yangyang Chen (Y)

Department of Mechanical & Aerospace Engineering, University of Missouri, Columbia, MO 65211.

Yun Ling (Y)

Department of Mechanical & Aerospace Engineering, University of Missouri, Columbia, MO 65211.

Peijun Guo (P)

Department of Chemical & Environmental Engineering, Yale University, West Haven, CT 06516.

Shinghua Ding (S)

Department of Biomedical, Biological & Chemical Engineering, University of Missouri, Columbia, MO 65211.
Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211.

Guoliang Huang (G)

Department of Mechanical & Aerospace Engineering, University of Missouri, Columbia, MO 65211.

Pai-Yen Chen (PY)

Department of Electrical and Computer Engineering, University of Illinois at Chicago, Chicago, IL 60607.

Qing Cao (Q)

Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801.

Zheng Yan (Z)

Department of Biomedical, Biological & Chemical Engineering, University of Missouri, Columbia, MO 65211; yanzheng@missouri.edu.
Department of Mechanical & Aerospace Engineering, University of Missouri, Columbia, MO 65211.

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Classifications MeSH