Myxoedema Coma Masquerading as Acute Stroke.
Myxoedema coma
hypothyroidism
thyroid emergencies
Journal
European journal of case reports in internal medicine
ISSN: 2284-2594
Titre abrégé: Eur J Case Rep Intern Med
Pays: Italy
ID NLM: 101648453
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
03
2020
accepted:
19
03
2020
entrez:
16
7
2020
pubmed:
16
7
2020
medline:
16
7
2020
Statut:
epublish
Résumé
This report describes the management of a patient with myxoedema coma masquerading as an acute stroke (with or without 'cold sepsis'). Myxoedema coma is an endocrine emergency occurring when physiological adaptations to untreated hypothyroidism are overwhelmed by an acute precipitant. Even promptly treated, it has an associated mortality of up to 50%. Early recognition of myxoedema coma is essential, however the chance of misdiagnosis remains high.Key management consists of rapid thyroid hormone replacement (intravenous T4 at 300-500 μg over 24 hours, followed by 50-100 μg daily), supportive measures and the concomitant management of triggers such as infection.
Identifiants
pubmed: 32665924
doi: 10.12890/2020_001563
pii: 1563-1-12919-1-10-20200421
pmc: PMC7350959
doi:
Types de publication
Journal Article
Langues
eng
Pagination
001563Informations de copyright
© EFIM 2020.
Déclaration de conflit d'intérêts
Conflicts of Interests: The Authors declare that there are no competing interests.
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