In Vitro Control of Genes Critical for Parathyroid Embryogenesis by Extracellular Calcium.
GATA3
GCM2
MAFB
calcium
parathyroid cells
parathyroid development
Journal
Journal of the Endocrine Society
ISSN: 2472-1972
Titre abrégé: J Endocr Soc
Pays: United States
ID NLM: 101697997
Informations de publication
Date de publication:
01 Jul 2020
01 Jul 2020
Historique:
received:
11
02
2020
accepted:
22
05
2020
entrez:
16
7
2020
pubmed:
16
7
2020
medline:
16
7
2020
Statut:
epublish
Résumé
The expression of the parathyroid transcription factors, encoded by the genes Adult adenoma parathyroid tissues were put in primary cell culture to evaluate the messenger ribonucleic acid (mRNA) expression of the The aim of the study was to investigate whether different extracellular calcium conditions could control the expression of transcription factors critical for parathyroid embryogenesis. The results of the experiments showed that the mRNA expression of These findings indicate that transcription factors recognized for their role in parathyroid embryogenesis show a response to extracellular calcium later in adulthood that parallels the behavior of the
Sections du résumé
BACKGROUND
BACKGROUND
The expression of the parathyroid transcription factors, encoded by the genes
MATERIALS AND METHODS
METHODS
Adult adenoma parathyroid tissues were put in primary cell culture to evaluate the messenger ribonucleic acid (mRNA) expression of the
AIM
OBJECTIVE
The aim of the study was to investigate whether different extracellular calcium conditions could control the expression of transcription factors critical for parathyroid embryogenesis.
RESULTS
RESULTS
The results of the experiments showed that the mRNA expression of
CONCLUSIONS
CONCLUSIONS
These findings indicate that transcription factors recognized for their role in parathyroid embryogenesis show a response to extracellular calcium later in adulthood that parallels the behavior of the
Identifiants
pubmed: 32666007
doi: 10.1210/jendso/bvaa058
pii: bvaa058
pmc: PMC7326476
doi:
Types de publication
Journal Article
Langues
eng
Pagination
bvaa058Informations de copyright
© Endocrine Society 2020.
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