Spectrum of Headaches Associated With SARS-CoV-2 Infection: Study of Healthcare Professionals.
Adult
COVID-19
/ complications
Comorbidity
Cross-Sectional Studies
Diabetes Mellitus
/ epidemiology
Dyslipidemias
/ epidemiology
Female
Gastrointestinal Diseases
/ etiology
Headache
/ classification
Headache Disorders, Secondary
/ diagnosis
Health Personnel
Humans
Hypertension
/ epidemiology
Male
Middle Aged
Migraine Disorders
/ epidemiology
Occupational Diseases
/ epidemiology
Pandemics
Personal Protective Equipment
Prevalence
SARS-CoV-2
Sensation Disorders
/ etiology
Spain
/ epidemiology
Surveys and Questionnaires
Tension-Type Headache
/ epidemiology
COVID-19
SARS-CoV-2
headache
healthcare professionals
migraine
neurological symptoms
Journal
Headache
ISSN: 1526-4610
Titre abrégé: Headache
Pays: United States
ID NLM: 2985091R
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
25
04
2020
revised:
17
06
2020
accepted:
18
06
2020
pubmed:
16
7
2020
medline:
22
12
2020
entrez:
16
7
2020
Statut:
ppublish
Résumé
Series of patients with SARS-CoV-2 infection report headache in 6%-15% of cases, although some data suggest that the actual frequency is higher, and that headache is not associated with fever. No study published to date has analyzed the characteristics of headache in these patients. To analyze the characteristics of COVID-19 related headaches. We conducted a survey of Spaniard healthcare professionals who have been infected by SARS-CoV-2 and presented headache during the course of the disease. The survey addressed respondents' medical history and headache characteristics, and we analyzed the association between both. We analyzed the responses of a sample of 112 healthcare professionals. History of migraine was reported by 20/112 (17.9%) of respondents, history of tension-type headache by 8/112 (7.1%), and history of cluster headache was reported by a single respondent; 82/112(73.2%) of respondents had no history of headache. Headache presented independently of fever, around the third day after symptom onset. The previous history of migraine was associated with a higher frequency of pulsating headache (20% in patients with previous migraine vs 4.3% in those with no history of migraine, P = .013). Headache is often holocranial, hemicranial, or occipital, pressing, and worsens with physical activity or head movements. Because the characteristics of the headache and the associated symptoms are heterogeneous in our survey, we suggest that several patterns with specific pathophysiological mechanisms may underlie the headache associated with COVID-19.
Sections du résumé
BACKGROUND
Series of patients with SARS-CoV-2 infection report headache in 6%-15% of cases, although some data suggest that the actual frequency is higher, and that headache is not associated with fever. No study published to date has analyzed the characteristics of headache in these patients.
OBJECTIVE
To analyze the characteristics of COVID-19 related headaches.
METHODS
We conducted a survey of Spaniard healthcare professionals who have been infected by SARS-CoV-2 and presented headache during the course of the disease. The survey addressed respondents' medical history and headache characteristics, and we analyzed the association between both.
RESULTS
We analyzed the responses of a sample of 112 healthcare professionals. History of migraine was reported by 20/112 (17.9%) of respondents, history of tension-type headache by 8/112 (7.1%), and history of cluster headache was reported by a single respondent; 82/112(73.2%) of respondents had no history of headache. Headache presented independently of fever, around the third day after symptom onset. The previous history of migraine was associated with a higher frequency of pulsating headache (20% in patients with previous migraine vs 4.3% in those with no history of migraine, P = .013).
CONCLUSION
Headache is often holocranial, hemicranial, or occipital, pressing, and worsens with physical activity or head movements. Because the characteristics of the headache and the associated symptoms are heterogeneous in our survey, we suggest that several patterns with specific pathophysiological mechanisms may underlie the headache associated with COVID-19.
Identifiants
pubmed: 32666513
doi: 10.1111/head.13902
pmc: PMC7405125
doi:
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1697-1704Informations de copyright
© 2020 American Headache Society.
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