Characteristics and determinants of patient burden and needs in the treatment of chronic spontaneous urticaria.
cross-sectional study
health-related quality of life
patient preferences
patient-reported outcome measures
quality of life
Journal
European journal of dermatology : EJD
ISSN: 1952-4013
Titre abrégé: Eur J Dermatol
Pays: France
ID NLM: 9206420
Informations de publication
Date de publication:
01 Jun 2020
01 Jun 2020
Historique:
entrez:
16
7
2020
pubmed:
16
7
2020
medline:
5
5
2021
Statut:
ppublish
Résumé
Treatment of chronic spontaneous urticaria (CSU) is founded on evidence-based guidelines. However, specific patient needs and benefits of therapy have not been outlined at the guideline level. The aim of this study was to characterise the specific needs and treatment goals in chronic spontaneous urticaria from the patient's perspective. This cross-sectional study was conducted in four German outpatient dermatology clinics. Patient needs and potential therapy goals were determined with the validated Patient Needs Questionnaire (PNQ) using a specific version for chronic urticaria. Further instruments to characterise the link between patient needs and disease burden were disease-specific (CU-Q2oL), skin-generic (DLQI) and health-generic (EQ VAS) scales. Data from 103 patients were analysed (age: 43.92 ± 14.96 years; 71.4% female). Among the most important therapeutic goals were the absence of visible skin lesions (92.3% important/very important), to be free of itching (91.5%) and the desire to be healed of all skin defects (89.5%). All 26 items were found to be quite important/very important by at least 30% of the respondents. Specific profiles of patient needs were found to be related to sex and disease duration. Innovative drugs and patient-centred individualised treatment may increase overall benefits. Regardless of the treatment chosen, shared decision making in the management of the disease should be a goal.
Sections du résumé
BACKGROUND
BACKGROUND
Treatment of chronic spontaneous urticaria (CSU) is founded on evidence-based guidelines. However, specific patient needs and benefits of therapy have not been outlined at the guideline level.
OBJECTIVES
OBJECTIVE
The aim of this study was to characterise the specific needs and treatment goals in chronic spontaneous urticaria from the patient's perspective.
MATERIALS AND METHODS
METHODS
This cross-sectional study was conducted in four German outpatient dermatology clinics. Patient needs and potential therapy goals were determined with the validated Patient Needs Questionnaire (PNQ) using a specific version for chronic urticaria. Further instruments to characterise the link between patient needs and disease burden were disease-specific (CU-Q2oL), skin-generic (DLQI) and health-generic (EQ VAS) scales.
RESULTS
RESULTS
Data from 103 patients were analysed (age: 43.92 ± 14.96 years; 71.4% female). Among the most important therapeutic goals were the absence of visible skin lesions (92.3% important/very important), to be free of itching (91.5%) and the desire to be healed of all skin defects (89.5%). All 26 items were found to be quite important/very important by at least 30% of the respondents. Specific profiles of patient needs were found to be related to sex and disease duration.
CONCLUSION
CONCLUSIONS
Innovative drugs and patient-centred individualised treatment may increase overall benefits. Regardless of the treatment chosen, shared decision making in the management of the disease should be a goal.
Identifiants
pubmed: 32666926
pii: ejd.2020.3763
doi: 10.1684/ejd.2020.3763
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM