An update on the RAPH blood group system.

Antigens, CD Blood Group Antigens / immunology Cell Adhesion Humans Integrin alpha3beta1 Tetraspanin 24

Journal

Immunohematology
ISSN: 0894-203X
Titre abrégé: Immunohematology
Pays: United States
ID NLM: 8806387

Informations de publication

Date de publication:
Jun 2020
Historique:
entrez: 16 7 2020
pubmed: 16 7 2020
medline: 9 9 2020
Statut: ppublish

Résumé

This update of the RAPH blood group system (Hayes M. RAPH blood group system. Immunohematology 2014;30:6-10) reports no new alleles. The RAPH blood group system (International Society of Blood Transfusion system 25) consists of a single anti-gen (MER2) expressed on CD151, a member of the tetraspanin family of proteins. CD151 regulates interactions with laminin-binding integrins α3β1, α6β1, α6β4, and α7β1 and is expressed on red blood cells as well as many other tissues and cancer types. Lack of the RAPH protein is associated with nephropathy with pretibial epidermolysis bullosa and deafness.

Identifiants

PMID: 32667818
pubmed: 32667818

Substances chimiques

Antigens, CD 0
Blood Group Antigens 0
Integrin alpha3beta1 0
Tetraspanin 24 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

58-59

Auteurs

Margaret A Keller (MA)

Senior Director, National Molecular Laboratory, American Red Cross.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Antigènes de différenciation › Antigènes CD › An update on the RAPH blood group system.
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes de groupe sanguin › An update on the RAPH blood group system.
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Adhérence cellulaire › An update on the RAPH blood group system.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › An update on the RAPH blood group system.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteur laminine › Intégrine alpha3 bêta1 › An update on the RAPH blood group system.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Tétraspanines › Antigène CD151 › An update on the RAPH blood group system.