Amitraz poisoning: Early gastric lavage can prevent life-threatening complications.
Amitraz
atropine
formamidine
gastric lavage
Journal
Journal of family medicine and primary care
ISSN: 2249-4863
Titre abrégé: J Family Med Prim Care
Pays: India
ID NLM: 101610082
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
30
12
2019
revised:
14
02
2020
accepted:
03
04
2020
entrez:
17
7
2020
pubmed:
17
7
2020
medline:
17
7
2020
Statut:
epublish
Résumé
Amitraz is a worldwide available pesticide of formamidine chemical family, proven to have reversible toxic effects on both animals and humans. Upon intoxication by ingestion, inhalation, or dermal route, it can cause various central nervous system (CNS), CVS, respiratory and gastrointestinal effects, some of which may be life threatening. Because of lack of specific antidote patients are usually managed with supportive and symptomatic management. We describe a case of 36-year-old female patient who presented to us with alleged history of 120 ml amitraz ingestion. She was given early gastric lavage with activated charcoal at emergency along with supportive and symptomatic management. She developed mild CNS depression, bradycardia, miosis, and fluctuating blood pressure. She was managed in intensive care unit and was kept under close hemodynamic monitoring. Her clinical course during hospital stay was uneventful and was successfully discharged without any residual deficits. According to previously published data, this amount of amitraz intoxication could have caused more serious clinical manifestations. This disproportionately less severe clinical manifestation in our patient is attributed to early gastric lavage. Ominous of reducing amitraz-related health hazards lies in the hands of primary health care physicians and regulatory bodies of government.
Identifiants
pubmed: 32670980
doi: 10.4103/jfmpc.jfmpc_1268_19
pii: JFMPC-9-2129
pmc: PMC7346969
doi:
Types de publication
Case Reports
Langues
eng
Pagination
2129-2131Informations de copyright
Copyright: © 2020 Journal of Family Medicine and Primary Care.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
Hum Exp Toxicol. 1997 Nov;16(11):680-2
pubmed: 9426371
BMJ Case Rep. 2015 Oct 01;2015:
pubmed: 26430228
Hum Exp Toxicol. 1997 Oct;16(10):600-1
pubmed: 9363478
J Vet Pharmacol Ther. 1998 Oct;21(5):400-5
pubmed: 9811442
Indian J Med Res. 2016 Sep;144(3):348-358
pubmed: 28139533
Hum Exp Toxicol. 2002 Jan;21(1):55-7
pubmed: 12046725
J Vet Pharmacol Ther. 1990 Mar;13(1):86-92
pubmed: 2157035
BMC Pharmacol Toxicol. 2017 Jan 23;18(1):6
pubmed: 28110639
Indian Pediatr. 2004 May;41(5):482-6
pubmed: 15181299