Stereotactic Radiotherapy for the Management of Refractory Ventricular Tachycardia: Promise and Future Directions.

ablation noninvasive radiotherapy stereotactic radiotherapy ventricular tachycardia

Journal

Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388

Informations de publication

Date de publication:
2020
Historique:
received: 23 03 2020
accepted: 22 05 2020
entrez: 17 7 2020
pubmed: 17 7 2020
medline: 17 7 2020
Statut: epublish

Résumé

Ventricular tachycardia (VT) caused by myocardial scaring bears a significant risk of mortality and morbidity. Antiarrhythmic drug therapy (AAD) and catheter ablation remain the cornerstone of VT management, but both treatments have limited efficacy and potential adverse effects. Stereotactic body radiotherapy (SBRT) is routinely used in oncology to treat non-invasively solid tumors with high precision and efficacy. Recently, this technology has been evaluated for the treatment of VT. This review presents the basic underlying principles, proof of concept, and main results of trials and case series that used SBRT for the treatment of VT refractory to AAD and catheter ablation.

Identifiants

pubmed: 32671101
doi: 10.3389/fcvm.2020.00108
pmc: PMC7329991
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

108

Informations de copyright

Copyright © 2020 Jumeau, Ozsahin, Schwitter, Elicin, Reichlin, Roten, Andratschke, Mayinger, Saguner, Steffel, Blanck, Vozenin, Moeckli, Zeverino, Vallet, Herrera-Siklody, Pascale, Bourhis and Pruvot.

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Auteurs

Raphael Jumeau (R)

Department of Radiation Oncology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Multidisciplinary Cancer Care Service, Radiation Oncology Unit, Riviera-Chablais Hospital, Rennaz, Switzerland.

Mahmut Ozsahin (M)

Department of Radiation Oncology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Juerg Schwitter (J)

Heart and Vessel Department, Cardiac MR Center, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Olgun Elicin (O)

Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.

Tobias Reichlin (T)

Department of Cardiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.

Laurent Roten (L)

Department of Cardiology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.

Nicolaus Andratschke (N)

Department of Radiation Oncology, University Hospital Zurich, Zürich, Switzerland.

Michael Mayinger (M)

Department of Radiation Oncology, University Hospital Zurich, Zürich, Switzerland.

Ardan M Saguner (AM)

Department of Cardiology, University Heart Center Zurich, Zürich, Switzerland.

Jan Steffel (J)

Department of Cardiology, University Heart Center Zurich, Zürich, Switzerland.

Oliver Blanck (O)

Department of Radiation Oncology and Department of Internal Medicine III, Cardiology, Section for Electrophysiology, University Medical Center Schleswig-Holstein, Kiel, Germany.

Marie-Catherine Vozenin (MC)

Radio-Oncology Research Laboratory, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Raphael Moeckli (R)

Institute of Radiation Physics, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Michele Zeverino (M)

Institute of Radiation Physics, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Véronique Vallet (V)

Institute of Radiation Physics, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Claudia Herrera-Siklody (C)

Heart and Vessel Department, Service of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Patrizio Pascale (P)

Heart and Vessel Department, Service of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Jean Bourhis (J)

Department of Radiation Oncology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Etienne Pruvot (E)

Heart and Vessel Department, Service of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Classifications MeSH