Usefulness of 500-m walk electrocardiogram test on clinical outcomes in patients with ST-segment elevation myocardial infarction.


Journal

Heart and vessels
ISSN: 1615-2573
Titre abrégé: Heart Vessels
Pays: Japan
ID NLM: 8511258

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 22 03 2020
accepted: 10 07 2020
pubmed: 17 7 2020
medline: 17 6 2021
entrez: 17 7 2020
Statut: ppublish

Résumé

The current Japanese guideline for ST-segment elevation myocardial infarction (STEMI) recommends 500-m walk electrocardiogram (ECG) test for patients with STEMI during hospitalization. However, little is known regarding the association between acute phase 500-m walk ECG test and clinical outcomes. The purpose of this study was to investigate the association between 500-m walk ECG test and mid-term clinical outcomes in patients with STEMI. A total of 313 STEMI patients who underwent primary percutaneous coronary interventions were included, and were divided into the successful 500-m group (n = 263) and the unsuccessful 500-m group (n = 50). The primary endpoint was the major adverse cardiovascular events (MACE), which were defined as the composite of all cause death, acute myocardial infarction, readmission for heart failure, and ischemia-driven target vessel revascularization (TVR). During the follow-up period (median 223 days), a total of 55 MACE were observed. The log-rank test revealed that MACE, all cause death, readmission for heart failure, and ischemia-driven TVR were more frequently observed in the unsuccessful 500-m group than the successful 500-m group. In the multivariate Cox proportional hazard model, the unsuccessful 500-m walk ECG test was significantly associated with MACE (OR 5.62, 95% CI 3.08-10.08, P < 0.01) after controlling confounding factors such as age, and serum creatinine levels. In conclusion, the unsuccessful 500-m walk ECG test was significantly associated with poor mid-term outcomes in patients with STEMI. Our results suggest the usefulness of 500-m walk ECG test to stratify the high-risk group from patients with STEMI.

Identifiants

pubmed: 32671463
doi: 10.1007/s00380-020-01667-0
pii: 10.1007/s00380-020-01667-0
doi:

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

48-57

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Auteurs

Jumpei Ohashi (J)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

Kenichi Sakakura (K)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan. ksakakura@jichi.ac.jp.

Wataru Sasaki (W)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

Yousuke Taniguchi (Y)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

Kunihiro Kani (K)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

Kei Yamamoto (K)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

Takunori Tsukui (T)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

Masaru Seguchi (M)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

Hiroshi Wada (H)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

Shin-Ichi Momomura (SI)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

Hideo Fujita (H)

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Omiya-ku, Amanuma, Saitama, 330-8503, Japan.

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