Functional linguistic specificity of the left frontal aslant tract for spontaneous speech fluency: Evidence from intraoperative language mapping.
Direct electrical stimulation
Frontal aslant tract
Spontaneous speech fluency
Tractography
Journal
Brain and language
ISSN: 1090-2155
Titre abrégé: Brain Lang
Pays: Netherlands
ID NLM: 7506220
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
11
12
2019
revised:
22
05
2020
accepted:
02
07
2020
pubmed:
17
7
2020
medline:
7
2
2021
entrez:
17
7
2020
Statut:
ppublish
Résumé
The left frontal aslant tract (FAT) has been proposed to be relevant for language, and specifically for spontaneous speech fluency. However, there is missing causal evidence that stimulation of the FAT affects spontaneous speech, and not language production in general. We present a series of 12 neurosurgical cases with awake language mapping of the cortex near the left FAT. Tasks for language mapping included the commonly used action picture naming, and sentence completion, tapping more specifically into spontaneous speech. A task dissociation was found in 10 participants: while being stimulated on specific sites, they were able to name a picture but could not complete a sentence. Overlaying of these sites on preoperative white-matter tract reconstructions revealed that in each individual case they were located on cortical terminations of the FAT. This corroborates the language functional specificity of the left FAT as a tract underlying fluent spontaneous speech.
Identifiants
pubmed: 32673898
pii: S0093-934X(20)30095-X
doi: 10.1016/j.bandl.2020.104836
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
104836Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.