Stem Cells: A Golden Therapy for Diabetic Wounds.
Diabetes mellitus
angiogenesis
diabetic complications
foot ulcer
stem cells
therapy
Journal
Current diabetes reviews
ISSN: 1875-6417
Titre abrégé: Curr Diabetes Rev
Pays: United Arab Emirates
ID NLM: 101253260
Informations de publication
Date de publication:
2021
2021
Historique:
received:
31
03
2020
revised:
27
06
2020
accepted:
28
06
2020
pubmed:
18
7
2020
medline:
19
3
2021
entrez:
18
7
2020
Statut:
ppublish
Résumé
Diabetes mellitus is the 7th leading cause of death worldwide. Diabetes can affect the organ systems and lead to serious complications, majorly categorized as macrovascular complications, microvascular complications, and diabetic wounds. Foot ulcer develops in 15-25% diabetic patients. In diabetic wound, there is an impairment in growth factor, neuropeptide, matrix metalloproteinases, angiogenesis, and immune system. Many approaches are being experimented to manage this major complication of diabetic foot, but unfortunately with lower success rate. Stem cell is an upcoming field which is being explored in the world of diabetes. Hence, this review is designed to understand the basic pathogenesis and complications of types of diabetes and the role of stem cells in a diabetic wound and the benefits related to it.
Identifiants
pubmed: 32674735
pii: CDR-EPUB-108215
doi: 10.2174/1573399816666200716200450
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
156-160Informations de copyright
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