European Society for Sexual Medicine Consensus Statement on the Use of the Cavernous Nerve Injury Rodent Model to Study Postradical Prostatectomy Erectile Dysfunction.
Animal Model
Cavernous Nerve
Erectile Dysfunction
Radical Prostatectomy
Journal
Sexual medicine
ISSN: 2050-1161
Titre abrégé: Sex Med
Pays: England
ID NLM: 101631053
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
16
03
2020
revised:
16
05
2020
accepted:
14
06
2020
pubmed:
18
7
2020
medline:
18
7
2020
entrez:
18
7
2020
Statut:
ppublish
Résumé
Rodent animal models are currently the most used in vivo model in translational studies looking into the pathophysiology of erectile dysfunction after nerve-sparing radical prostatectomy. This European Society for Sexual Medicine (ESSM) statement aims to guide scientists toward utilization of the rodent model in an appropriate, timely, and proficient fashion. MEDLINE and EMBASE databases were searched for basic science studies, using a rodent animal model, looking into the consequence of pelvic nerve injury on erectile function. The authors present a consensus on how to best perform experiments with this rodent model, the details of the technique, and highlight possible pitfalls. Owing to the specific issue-basic science-Oxford 2011 Levels of Evidence criteria cannot be applied. However, ESSM statements on this topic will be provided in which we summarize the ESSM position on various aspects of the model such as the use of the Animal Research Reporting In Vivo Experiments guideline and the of common range parameter for nerve stimulation. We also highlighted the translational limits of the model. The following statements were formulated as a suggestive guidance for scientists using the cavernous nerve injury model. With this, we hope to standardize and further improve the quality of research in this field. It must be noted that this model has its limitations. Weyne E, Ilg MM, Cakir OO, et al. European Society for Sexual Medicine Consensus Statement on the Use of the Cavernous Nerve Injury Rodent Model to Study Postradical Prostatectomy Erectile Dysfunction. Sex Med 2020;8:327-337.
Identifiants
pubmed: 32674971
pii: S2050-1161(20)30083-0
doi: 10.1016/j.esxm.2020.06.007
pmc: PMC7471127
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
327-337Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.
Références
J Reprod Fertil. 1982 Nov;66(2):433-43
pubmed: 7175800
Eur Urol. 2014 Apr;65(4):673-4
pubmed: 24388439
J Sex Med. 2014 Jun;11(6):1442-51
pubmed: 24636283
PLoS One. 2009 Nov 30;4(11):e7824
pubmed: 19956596
J Sex Med. 2008 Aug;5(8):1949-54
pubmed: 18466264
Biol Reprod. 1975 Mar;12(2):289-92
pubmed: 1122335
Korean J Urol. 2011 Aug;52(8):560-5
pubmed: 21927704
J Urol. 2013 Mar;189(3):854-9
pubmed: 23022004
Biol Reprod. 1998 Dec;59(6):1413-8
pubmed: 9828186
Sci Rep. 2017 Dec 19;7(1):17819
pubmed: 29259207
Eur Urol. 2011 Nov;60(5):1020-6
pubmed: 21839578
Int J Prev Med. 2013 Jun;4(6):624-30
pubmed: 23930179
J Urol. 1998 Dec;160(6 Pt 1):2245-52
pubmed: 9817378
Int J Urol. 2003 May;10(5):251-6
pubmed: 12694464
Eur Urol. 2012 Dec;62(6):1076-85
pubmed: 22542670
Nat Rev Urol. 2019 Feb;16(2):79-97
pubmed: 30367131
Drug Discov Today. 2006 Apr;11(7-8):355-63
pubmed: 16580978
Mol Med. 1996 May;2(3):288-96
pubmed: 8784782
Cancer. 2016 Feb 15;122(4):626-33
pubmed: 26540451
Int J Impot Res. 2001 Apr;13(2):82-8
pubmed: 11426343
J Urol. 2000 Jun;163(6):1992-8
pubmed: 10799245
Childs Nerv Syst. 2015 Feb;31(2):177-80
pubmed: 25269543
Biochem Biophys Res Commun. 1990 Jul 31;170(2):843-50
pubmed: 2166511
BJU Int. 2018 Dec;122(6):1066-1074
pubmed: 29888556
Am J Physiol. 1988 Jun;254(6 Pt 2):R989-1000
pubmed: 3381920
J Urol. 1989 Jun;141(6):1444-8
pubmed: 2566691
Curr Drug Targets. 2015;16(5):459-73
pubmed: 25777276
Nature. 2012 Oct 11;490(7419):187-91
pubmed: 23060188
J Sex Med. 2011 Dec;8(12):3291-305
pubmed: 21981717
J Sex Med. 2012 Feb;9(2):608-17
pubmed: 22189164
Int J Urol. 2009 Nov;16(11):905-11
pubmed: 19780868
J Urol. 1989 Mar;141(3):656-61
pubmed: 2918611
Br J Urol. 1988 Jun;61(6):510-5
pubmed: 3135873
Transl Androl Urol. 2015 Aug;4(4):421-37
pubmed: 26816841
J Sex Med. 2009 Mar;6 Suppl 3:340-6
pubmed: 19267858
Br J Pharmacol. 2001 Nov;134(6):1190-4
pubmed: 11704638
J Urol. 2004 Jan;171(1):495-500
pubmed: 14665962
J Urol. 2000 Dec;164(6):1929-34
pubmed: 11061884
J Clin Invest. 1991 Jul;88(1):112-8
pubmed: 1647413
J Auton Nerv Syst. 1995 Oct 5;55(1-2):36-44
pubmed: 8690849
J Sex Med. 2015 Mar;12(3):590-9
pubmed: 25529966
J Sex Med. 2017 Feb;14(2):187-195
pubmed: 28161077
Eur Urol. 2018 Mar;73(3):482-484
pubmed: 29150358
Am J Physiol. 1993 Feb;264(2 Pt 2):H419-22
pubmed: 8383456
J Androl. 2000 Mar-Apr;21(2):311-5
pubmed: 10714826
Curr Urol Rep. 2017 Sep 30;18(11):90
pubmed: 28965315
Acta Physiol Scand. 1995 Dec;155(4):445-55
pubmed: 8719264
Biol Reprod. 1994 Aug;51(2):234-8
pubmed: 7948478
Br J Pharmacol. 1999 May;127(2):349-60
pubmed: 10385233
Int J Impot Res. 2002 Aug;14(4):251-5
pubmed: 12152113
J Physiol. 1999 Apr 1;516 ( Pt 1):261-9
pubmed: 10066939
BJU Int. 2019 Aug;124(2):342-348
pubmed: 30267556
Sex Med Rev. 2018 Apr;6(2):234-241
pubmed: 28827037
J Sex Med. 2008 Aug;5(8):1776-85
pubmed: 18774987
BJU Int. 2013 Nov;112(7):998-1008
pubmed: 23826962
Prog Urol. 1996 Feb;6(1):81-6
pubmed: 8624532
J Sex Med. 2014 Jul;11(7):1685-93
pubmed: 24831646
Pharmacol Rev. 2011 Dec;63(4):811-59
pubmed: 21880989
J Sex Med. 2010 Oct;7(10):3331-40
pubmed: 20561166
Urology. 1995 Jul;46(1):85-8
pubmed: 7604482
BJU Int. 1999 Aug;84(3):305-10
pubmed: 10468727
Eur Urol. 2010 Feb;57(2):179-92
pubmed: 19931974
Urology. 1984 Oct;24(4):347-52
pubmed: 6485194
J Sex Med. 2009 May;6(5):1270-83
pubmed: 19210708
Am J Physiol. 1998 Aug;275(2):H600-8
pubmed: 9683449
J Physiol. 1987 Mar;384:525-38
pubmed: 3656155
Am J Physiol Regul Integr Comp Physiol. 2007 Mar;292(3):R1359-67
pubmed: 17095649
Am J Vet Res. 1975 Apr;36(4 Pt.1):431-3
pubmed: 1124879
Biol Reprod. 1992 Mar;46(3):342-8
pubmed: 1617008
Am J Physiol. 1998 Apr;274(4):H1075-81
pubmed: 9575909
Int J Urol. 2013 Apr;20(4):413-9
pubmed: 22970988
Hypertens Res. 2009 Aug;32(8):685-9
pubmed: 19498439
J Sex Med. 2012 Feb;9(2):385-403
pubmed: 22145667
Am J Physiol. 1995 Oct;269(4 Pt 2):R904-13
pubmed: 7485610
Eur Urol. 2016 Dec;70(6):1032-1041
pubmed: 27156445
J Auton Nerv Syst. 1992 Dec;41(3):221-6
pubmed: 1289386
Acta Physiol Scand. 1991 Nov;143(3):299-304
pubmed: 1722938
Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2349-54
pubmed: 10688876
Nat Rev Urol. 2015 May;12(5):289-97
pubmed: 25868558
J Urol. 2012 Feb;187(2):757-63
pubmed: 22177198
J Sex Med. 2010 Oct;7(10):3351-64
pubmed: 20646178
J Sex Med. 2008 May;5(5):1126-1136
pubmed: 18331274
Curr Opin Urol. 2016 Mar;26(2):129-39
pubmed: 26759972
J Sex Med. 2012 Nov;9(11):2770-84
pubmed: 22974227
J Urol. 1990 Sep;144(3):794-7
pubmed: 2388352
J Sex Med. 2006 Jan;3(1):77-83
pubmed: 16409220
J Sex Med. 2016 Dec;13(12):1844-1857
pubmed: 27864032
Br J Pharmacol. 2001 Mar;132(6):1333-41
pubmed: 11250885
BJU Int. 2013 Mar;111(3):412-8
pubmed: 22703190
Sex Med. 2019 Mar;7(1):94-103
pubmed: 30503767
BJU Int. 2004 Oct;94(6):904-9
pubmed: 15476533
Physiol Behav. 2007 Aug 15;91(5):535-43
pubmed: 17512960
Am J Physiol. 1976 Nov;231(5 Pt. 1):1343-8
pubmed: 998776
Int J Impot Res. 2020 May;32(3):281-288
pubmed: 30988428
J Sex Med. 2010 Sep;7(9):2970-95
pubmed: 21050395
Neurourol Urodyn. 2011 Jun;30(5):636-46
pubmed: 21661007
Physiol Behav. 1991 Jun;49(6):1235-46
pubmed: 1896506
J Sex Med. 2012 Jul;9(7):1834-41
pubmed: 22548750
J Sex Med. 2016 Jan;13(1):1-11
pubmed: 26755080
J Urol. 2013 Jun;189(6):2364-70
pubmed: 23219540
World J Urol. 2013 Apr;31(2):275-80
pubmed: 22441310
Neurourol Urodyn. 2001;20(2):197-210; discussion 210-3
pubmed: 11170194
Eur Urol. 2015 Aug;68(2):216-25
pubmed: 25770484
J Urol. 1995 Oct;154(4):1426-8
pubmed: 7658549
Endocrine. 2004 Mar-Apr;23(2-3):93-100
pubmed: 15146085