Targeting the cancer lesion, not the whole prostate.
Prostate cancer
cryotherapy
focal brachytherapy
focal radiofrequency ablation (focal RFA)
focal therapy
high-intensity focused ultrasound (HIFU)
index lesion
irreversible electroporation (IRE)
laser interstitial therapy (LITT)
photodynamic therapy (PDT)
vascular-targeted photodynamic therapy (VTP)
Journal
Translational andrology and urology
ISSN: 2223-4691
Titre abrégé: Transl Androl Urol
Pays: China
ID NLM: 101581119
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
entrez:
18
7
2020
pubmed:
18
7
2020
medline:
18
7
2020
Statut:
ppublish
Résumé
Modern cancer treatment aims to conserve as much healthy tissue as possible. This has been challenging in the treatment of prostate cancer due to the difficulty in imaging the gland and concerns over leaving multifocal cancer untreated. With improvements in imaging and understanding of multifocal prostate cancer evidence now shows accurate treatment of just the primary focus of cancer or the index lesion can control progression or recurrence of the disease. Many different energy sources are now available to target the cancer lesion within the prostate with less significant side-effects on urinary and sexual function compared to radical treatment. Evidence shows that men value these functions highly and would even trade years of life in exchange for preserved retention of continence or erectile function. Focal treatment of prostate cancer aims to provide both cancer control and preservation of sexual and urinary functions so that men do not have to make a choice between the two. This is a treatment option that men clearly want and deserve.
Identifiants
pubmed: 32676439
doi: 10.21037/tau.2019.09.12
pii: tau-09-03-1518
pmc: PMC7354301
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1518-1525Subventions
Organisme : Wellcome Trust
ID : 204998/Z/16/Z
Pays : United Kingdom
Informations de copyright
2020 Translational Andrology and Urology. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/tau.2019.09.12). The series “Prostate Imaging and Focal Therapy” was commissioned by the editorial office without any funding or sponsorship. HUA served as an unpaid Guest Editor of the series. DR is a clinical research fellow funded by a research grant from Prostate Cancer UK. HUA reports grants and personal fees from Sonacare, grants and personal fees from Boston Scientific, grants and personal fees from Sophiris Biocorp, grants from Trod medical, NB has no other conflicts of interest to declare.
Références
Cancer. 2009 May 15;115(10):2104-10
pubmed: 19288576
Nature. 2015 Apr 16;520(7547):353-357
pubmed: 25830880
Eur Urol. 2017 Feb;71(2):267-273
pubmed: 27720531
N Engl J Med. 2018 Dec 13;379(24):2319-2329
pubmed: 30575473
J Urol. 2007 Dec;178(6):2260-7
pubmed: 17936815
Eur Urol. 2017 Jan;71(1):17-34
pubmed: 27595377
BJU Int. 2013 Oct;112(6):766-74
pubmed: 24028764
Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):903-911
pubmed: 29510957
Cancer Treat Rev. 2016 Dec;51:27-34
pubmed: 27846402
Anticancer Res. 2009 Dec;29(12):5155-61
pubmed: 20044631
World J Urol. 2016 May;34(5):657-64
pubmed: 26296371
J Natl Cancer Inst Monogr. 2012 Dec;2012(45):184-90
pubmed: 23271771
BJU Int. 2010 Dec;106(11):1607-11
pubmed: 20553262
BJU Int. 2016 Jul;118(1):7
pubmed: 27311545
Eur Urol. 2015 Dec;68(6):924-6
pubmed: 25979568
Transl Androl Urol. 2018 Feb;7(1):83-97
pubmed: 29594023
Eur Urol. 2014 Oct;66(4):732-51
pubmed: 23769825
Ther Adv Urol. 2012 Aug;4(4):155-60
pubmed: 22852025
Curr Opin Endocrinol Diabetes Obes. 2013 Jun;20(3):204-9
pubmed: 23609043
J Endourol. 2016 Jan;30(1):43-8
pubmed: 26414656
Cochrane Database Syst Rev. 2019 Apr 25;4:CD012663
pubmed: 31022301
JAMA. 2009 Oct 21;302(15):1685-92
pubmed: 19843904
Curr Opin Urol. 2012 May;22(3):203-9
pubmed: 22472510
Lancet Oncol. 2012 Nov;13(11):e509-17
pubmed: 23117005
J Urol. 2012 Oct;188(4):1151-6
pubmed: 22901567
Contemp Clin Trials. 2013 Sep;36(1):68-80
pubmed: 23774040
Prostate Cancer Prostatic Dis. 2014 Dec;17(4):343-7
pubmed: 25179590
Cancer Chemother Rep. 1966 Mar;50(3):125-8
pubmed: 5948714
J Endourol. 2017 Jun;31(6):564-571
pubmed: 28385075
N Engl J Med. 2016 Oct 13;375(15):1415-1424
pubmed: 27626136
Eur Urol. 2012 Jul;62(1):55-63
pubmed: 22445223
Br J Urol. 1998 Feb;81(2):265-75
pubmed: 9488071
Eur Urol. 2016 Jun;69(6):973-5
pubmed: 26778462
J Urol. 2009 Oct;182(4):1371-7
pubmed: 19683262
Eur Urol. 2010 Sep;58(3):369-73
pubmed: 20478652
Eur Urol. 2018 Oct;74(4):422-429
pubmed: 29960750
J Urol. 2020 Jan 22;:101097JU0000000000000754
pubmed: 31967521
Eur Urol Focus. 2019 Nov;5(6):1022-1028
pubmed: 29661587
N Engl J Med. 2017 Jul 13;377(2):132-142
pubmed: 28700844
N Engl J Med. 2018 May 10;378(19):1767-1777
pubmed: 29552975
Urol Clin North Am. 2017 Nov;44(4):575-585
pubmed: 29107274
Am J Surg Pathol. 1993 May;17(5):468-72
pubmed: 8470761
Eur Urol. 2019 Jul;76(1):98-105
pubmed: 30638633
Oncology (Williston Park). 2014 Jan;28(1):16-22
pubmed: 24683714
J Urol. 2015 Apr;193(4):1185-90
pubmed: 25463987
Lancet Oncol. 2017 Feb;18(2):181-191
pubmed: 28007457
Health Econ. 2007 Jul;16(7):703-17
pubmed: 17238221
N Engl J Med. 2009 Oct 22;361(17):1704-6
pubmed: 19846858
Am J Surg Pathol. 2005 Sep;29(9):1228-42
pubmed: 16096414
Nat Med. 2009 May;15(5):559-65
pubmed: 19363497
Nat Rev Urol. 2016 Sep;13(9):541-8
pubmed: 27530265
Prostate Cancer Prostatic Dis. 2016 Mar;19(1):46-52
pubmed: 26458959
Eur Urol. 2017 Jul;72(1):e15-e16
pubmed: 28089305
Brachytherapy. 2013 Jul-Aug;12(4):331-7
pubmed: 23601349