On the Bioactivity and Mechanical Properties of Gehlenite Nanobioceramic: A Comparative Study.
Bioactivity
gehlenite
hydroxyapatite
mechanical properties
Journal
Journal of medical signals and sensors
ISSN: 2228-7477
Titre abrégé: J Med Signals Sens
Pays: India
ID NLM: 101577416
Informations de publication
Date de publication:
Historique:
received:
19
08
2019
revised:
12
10
2019
accepted:
30
01
2020
entrez:
18
7
2020
pubmed:
18
7
2020
medline:
18
7
2020
Statut:
epublish
Résumé
For a new biomaterial which is going to be applied in bone tissue regeneration, bioactivity (bone bonding ability) and desirable mechanical properties are very essential parameters to take into consideration. In the present study, the gehlenite's mechanical properties and bioactivity are assessed and compared with hydroxyapatite (HA) for bone tissue regeneration. Gehlenite and HA nanoparticles are synthesized through sol-gel method and coprecipitation technique, respectively, and their physical and chemical properties are characterized through X-ray diffraction, Fourier transform infrared spectroscopy, and transmission electron microscopy. The results prove that the gehlenite and HA phases without any undesirable phase are obtained, and the particles of both compounds are in the nanometer range with spherical morphology. The compressive strength of both compounds are assessed, and the values for gehlenite and HA disks are 144 ± 5 and 150 ± 4.8 MPa, respectively. Next, their bioactivity potential is assessed into simulated body fluid (SBF) up to 21 days, and the results show that after 14 days, gehlenite disk's surface is completely covered with newly formed Ca-P particles. However, some sporadic precipitations after 21 days soaking into SBF are formed onto the HA disk's surface. This comparative study shows that nanostructured gehlenite disk with desirable mechanical properties and faster bioactivity kinetic than HA can be considered as a promising bioceramic for bone tissue regeneration.
Sections du résumé
BACKGROUND
BACKGROUND
For a new biomaterial which is going to be applied in bone tissue regeneration, bioactivity (bone bonding ability) and desirable mechanical properties are very essential parameters to take into consideration. In the present study, the gehlenite's mechanical properties and bioactivity are assessed and compared with hydroxyapatite (HA) for bone tissue regeneration.
METHOD
METHODS
Gehlenite and HA nanoparticles are synthesized through sol-gel method and coprecipitation technique, respectively, and their physical and chemical properties are characterized through X-ray diffraction, Fourier transform infrared spectroscopy, and transmission electron microscopy.
RESULTS
RESULTS
The results prove that the gehlenite and HA phases without any undesirable phase are obtained, and the particles of both compounds are in the nanometer range with spherical morphology. The compressive strength of both compounds are assessed, and the values for gehlenite and HA disks are 144 ± 5 and 150 ± 4.8 MPa, respectively. Next, their bioactivity potential is assessed into simulated body fluid (SBF) up to 21 days, and the results show that after 14 days, gehlenite disk's surface is completely covered with newly formed Ca-P particles. However, some sporadic precipitations after 21 days soaking into SBF are formed onto the HA disk's surface.
CONCLUSION
CONCLUSIONS
This comparative study shows that nanostructured gehlenite disk with desirable mechanical properties and faster bioactivity kinetic than HA can be considered as a promising bioceramic for bone tissue regeneration.
Identifiants
pubmed: 32676446
doi: 10.4103/jmss.JMSS_41_19
pii: JMSS-10-105
pmc: PMC7359955
doi:
Types de publication
Journal Article
Langues
eng
Pagination
105-112Informations de copyright
Copyright: © 2020 Journal of Medical Signals & Sensors.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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